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The penultimate event in the intoxication of mammalian cells by ricin toxin is the reduction, in the endoplasmic reticulum (ER… Expand Locked nucleic acids (LNAs) are modified nucleic acids which contain a modified sugar such as beta-D-2'-O,4'-C methylene-bridged… Expand AIM
To investigate the therapeutic potential of an RNA ligand (aptamer) specific for the catalytic ricin A-chain (RTA), the… Expand PURPOSE
To examine force generation and duration of effect of botulinum toxin pretreatment, followed by injection of ricin-mAb35… Expand Ricin, a lectin from the castor bean plant (Ricinis communis), is considered one of the most potent plant toxins. Ingestion of… Expand The effect of moisture content and film composition on biodegradability is the focus of this study. Flexible films were first… Expand Purpose: The authors recently demonstrated that a single injection of the immunotoxin ricin-mAb35 has potent and long-lasting… Expand Purpose. To identify acute histologic change of extraocular muscles induced by bupivacaine or ricin mAb 35 injection. Methods… Expand In patients with small‐cell lung cancer (SCLC), relapse with resistant disease often causes death. N901‐blocked ricin (N901‐bR… Expand After complete cleavage of ricin interchain disulfide bridge by 0.05 M dithiothreitol in nondenaturing conditions at 37 degrees C… Expand