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'Pseudohypertriglyceridemia' caused by hyperglycerolemia due to congenital enzyme deficiency.
TLDR
A 76-year-old man was found to have a false hypertriglyceridemia due to a 40-fold increased glycerolemia because of a deficiency in glycerol kinase, and the small number of this family's members did not allow to specify the mode of transmission of this genetic trait. Expand
Characterization of N-linked oligosaccharides of an HLA-DR molecule expressed in different cell lines.
TLDR
Investigation of the N-glycosylation of a molecule of the human major histocompatibility complex (MHC) class II, the HLA-DR antigen, found differences were noticed within the same molecule, showing the importance of the individual peptide backbone for the glycosylations process. Expand
Dictyostelium discoideum cells shed vesicles with associated DNA and vital stain Hoechst 33342
TLDR
It is shown that D. discoideum cells vitally stained with the DNA-specific dye, Hoechst 33342, release fluorescent material in their culture medium, and it is proposed that these extracellular vesicles are involved in a new cellular resistance mechanism against xenobiotics. Expand
Carbamazepine directly inhibits adipocyte differentiation through activation of the ERK 1/2 pathway
TLDR
This work tested the hypothesis that CBZ could have a direct effect on adipocyte development and metabolism and found it to be plausible. Expand
Lipoprotein(a) in Diabetic Patients and Normoglycemic Relatives in Familial NIDDM
TLDR
High Lp(a) levels seem to be an independent risk factor for myocardial infarction in this NIDDM cohort, and was not related to the degree of glucose intolerance, but presented a strong familial aggregation. Expand
In adrenocortical tissue, annexins II and VI are attached to clathrin coated vesicles in a calcium-independent manner.
TLDR
It is shown that annexins II and VI, two of the annexins involved in membrane traffic, are present in the three populations of CCVs but with different distributions between coat proteins and lipidic vesicle membrane. Expand
Uptake of injected 125I-ricin by rat liver in vivo. Subcellular distribution and characterization of the internalized ligand.
TLDR
It is concluded that internalized ricin associates with endocytic structures whose size and density of equilibration increase with time, and that, although detectable in these structures, reduction of the ricin interchain disulphide bridge occurs to a large extent in the cytosol. Expand
Interactions of ricin with sinusoidal endothelial rat liver cells. Different involvement of two distinct carbohydrate-specific mechanisms in surface binding and internalization.
TLDR
Interactions of the plant toxin ricin with sinusoidal endothelial rat liver cells (EC) are investigated and retroendocytosis occurs after internalization of ricin via either pathway and to a much greater extent than for other glycoproteins taken up via mannose receptors of the EC. Expand
Separation of ricin A- and B-chains after dithiothreitol reduction.
TLDR
A- and B-chains have been characterized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunology and their specific activities have been tested by protein synthesis inhibition in a cell-free assay and on whole cells and by hemagglutination. Expand
Binding and internalization of ricin labelled with fluorescein isothiocyanate.
TLDR
Fluorescence microscopy provides preliminary evidence for secondary endosomes in the cytoplasm and lateral diffusion coefficient of cell surface bound ricin is studied by fluorescence photobleaching recovery. Expand
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