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Ricin A Chain

Known as: A Chain, Ricin 
One of the two glycoprotein disulfide-linked chains of Ricinus Communis Agglutin II that causes protein synthesis inhibition and cell death. (NCI)
National Institutes of Health

Papers overview

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2005
2005
Proteins that fail to fold in the endoplasmic reticulum (ER) or cannot find a pattern for assembly are often disposed of by a… 
Highly Cited
1995
Highly Cited
1995
We have used covalent coupling of deglycosylated ricin A chain (RAC) to the assembly initiation/translational repression RNA stem… 
Highly Cited
1995
Highly Cited
1995
Indirect immunofluorescence studies revealed that when fixed, permeabilized cultured human cells were incubated with ricin A… 
Highly Cited
1993
Highly Cited
1993
An Escherichia coli expression system was used to produce recombinant ricin A chain (RTA) and RTA modified either by the addition… 
Highly Cited
1992
Highly Cited
1992
Active site residues of ricin A chain were analyzed by site-directed mutagenesis and X-ray diffraction to help assess their roles… 
Highly Cited
1989
Highly Cited
1989
When recombinant ricin A chain transcripts are translated in a rabbit reticulocyte lysate the ribosomes are rapidly inactivated… 
Highly Cited
1989
Highly Cited
1989
mAb 907 is directed against the envelope protein of the HIV. The epitope recognized by this antibody is expressed in moderate… 
1988
1988
An immunotoxin (IT) was prepared from monoclonal antibody (MoAb) 115D8 and ricin A chain. MoAb 115D8 is directed against the… 
Highly Cited
1984
Highly Cited
1984
Pokeweed antiviral protein (PAP) and ricin A chain are potent inhibitors of protein synthesis that inactivate eukaryotic 60S… 
Highly Cited
1982
Highly Cited
1982
The toxic subunit of ricin has been conjugated by a disulfide bound to a monoclonal murine antibody (J-5) specific for the common…