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anginex peptide

 
National Institutes of Health

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Peptides

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2018
2018
Combination of anginex gene therapy and radiation decelerates the growth and pulmonary metastasis of human osteosarcoma xenografts
Abstract Investigate whether rAAV‐anginex gene therapy combined with radiotherapy could decrease growth and pulmonary metastasis… Expand
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2016
2016
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Anginex is an artificial synthetic small molecule β-sheet-forming peptide shown to have anti-angiogenesis and antitumor effects… Expand
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2014
2014
Anginex lipoplexes for delivery of anti-angiogenic siRNA.
Angiogenesis is one of the hallmarks of cancer which renders it an attractive target for therapy of malignancies. Tumor growth… Expand
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2013
2013
In vitro Characterization of a Lipidic Delivery System for Anti-angiogenic siRNA
SUMMARY In this study, Anginex lipoplexes (AxL) were developed for intracellular delivery of non-coding RNA (ncRNA) to… Expand
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2012
2012
Radiation-induced galectin-1 by endothelial cells: a promising molecular target for preferential drug delivery to the tumor vasculature
The present study reports on a new strategy for selective, radiation therapy-amplified drug delivery using an antiangiogenic 33-a… Expand
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2005
2005
Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells.
We have demonstrated that the designed peptide anginex displays potent antiangiogenic activity. The aim of our study was to… Expand
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