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ametantrone

Known as: 9, 10-Anthracenedione, 1, 4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, HAQ, 1,4-bis[[2-[(2-Hydroxyethyl)amino]ethyl]amino]9,10-anthracenedione 
A topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA of tumor cells.
National Institutes of Health

Related topics

Related topics

9 relations
Ametantrone AcetateDNA Breaks, Double-StrandedDNA IntercalationNCIt Antineoplastic Agent Terminology

Broader (3)

Antineoplastic AgentsIntercalating AgentsMitoxantrone

Narrower (1)

NSC 287513

Papers overview

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2016
2016
Optimizing biologic therapy in rheumatology: frequency and characteristics from an argentine referral centre
Background: Treatment strategy after achieving sustained remission in rheumatic conditions remains uncertain. Objetives: to… 
2015
2015
Effect of Combined Garlic Therapy and Comprehensive Rehabilitation Program versus Comprehensive Rehabilitation Program Alone on Control of Clinical Manifestations and Quality of Life of Knee…
Objective: To compare the effect of comprehensive rehabilitation program versus combined garlic therapy and comprehensive… 
2014
2014
he relationship between hemoglobin level and isease activity in patients with rheumatoid
Objectives: This study aims to investigate the relationship of hemoglobin level with disease activity in patients with rheumatoid… 
2013
2013
The Effects of Sex on Patient Reported Outcomes in Inflammatory Arthritis and Connective Tissue Diseases
Background: It was thought that women report higher pain than men. We studied if there was a sex difference for several patient… 
2012
2012
Valor de corte de HAQ para predecir discapacidad laboral en pacientes con artritis reumatoidea
La discapacidad laboral ocurre de forma temprana en pacientes con Artritis Reumatoidea (AR), con un importante impacto… 
2002
2002
HAQ (=Health Assessment Questionnaire) Scores of Out-Patients in a Clinic for Physical Medicine
SUMMARY The level of activity was assessed in 334 out-patients who visited the Clinic of Physical Medicine at the… 
1996
1996
Should the MHAQ ever be used?
tests. The MHAQ total scores were on average 31-5% lower than those of the full HAQ (1-49 (SD 074) for the HAQ and 1-02 (1-00… 
1985
1985
Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.
The anthracenedione antineoplastic agents mitoxantrone and ametantrone are potent inhibitors of basal and drug-stimulated lipid… 
1983
1983
Phase I investigation of ametantrone.
Ametantrone is the third of a family of anthracene derivatives to undergo a phase I trial in man. Sixteen patients received 33… 
1980
1980
Pharmacological disposition of 1,4-bis (2-[(2-hydroxyethyl)amino]-ethylamino)-9,10-anthracenedione diacetate in the dog.
1,4-Bis (2-[(2-hydroxyethyl)amino]ethylamino)-9,10-anthracenedione (NSC 287513) (HAQ) may be selected for clinical trial based on…