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alpha-methyldopamine
Known as:
3,4-dihydroxyamphetamine
, catecholamphetamine
, alpha methyldopamine
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Catecholamines
Deoxyepinephrine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Neurotoxicity mechanisms of thioether ecstasy metabolites
J. Capela
,
Camila de Cássia Macedo
,
+8 authors
F. Carvalho
Neuroscience
2007
Corpus ID: 26066691
Review
2004
Review
2004
The Role of Metabolism in 3,4-(±)-Methylenedioxyamphetamine and 3,4-(±)-Methylenedioxymethamphetamine (Ecstasy) toxicity
T. Monks
,
Douglas C. Jones
,
F. Bai
,
S. Lau
Therapeutic Drug Monitoring
2004
Corpus ID: 20230443
Abstract: 3,4-Methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) are ring-substituted…
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Highly Cited
2004
Highly Cited
2004
The toxicity of N-methyl-α-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine
M. Carvalho
,
F. Remião
,
+4 authors
M. Bastos
2004
Corpus ID: 13210028
Highly Cited
1999
Highly Cited
1999
Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
F. Bai
,
S. Lau
,
T. Monks
Chemical Research in Toxicology
1999
Corpus ID: 796870
Direct injection of either 3,4-(+/-)-methylenedioxymethamphetamine (MDMA) or 3,4-(+/-)-methylenedioxyamphetamine (MDA) into the…
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Highly Cited
1996
Highly Cited
1996
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
H. Helmlin
,
K. Bracher
,
D. Bourquin
,
David Vonlanthen
,
Rudolf Brenneisen
,
Juraj Styk
Journal of Analytical Toxicology
1996
Corpus ID: 23885210
In Europe, the compound 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy, Adam), in addition to cannabis, is the most abused…
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Highly Cited
1996
Highly Cited
1996
Metabolism of racemic 3,4-methylenedioxyethylamphetamine in humans. Isolation, identification, quantification, and synthesis of urinary metabolites.
H. Ensslin
,
Hans H. Maurer
,
Euphrosyne Gouzoulis
,
Leo Hermle
,
K. Kovar
Drug Metabolism And Disposition
1996
Corpus ID: 28725216
Studies on the isolation, identification, quantification, and synthesis of the urinary metabolites of racemic 3,4…
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Highly Cited
1996
Highly Cited
1996
Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-alpha-methyldopamine on brain dopamine, serotonin, and norepinephrine concentrations in male Sprague-Dawley rats.
R. T. Miller
,
S. Lau
,
T. Monks
Chemical Research in Toxicology
1996
Corpus ID: 24165628
alpha-Methyldopamine (alpha-MeDA) is a metabolite of the serotonergic neurotoxicants 3,4-(+/-)-(methylenedioxy)amphetamine (MDA…
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Highly Cited
1993
Highly Cited
1993
Clearance of Exogenous Dopamine in Rat Dorsal Striatum and Nucleus Accumbens: Role of Metabolism and Effects of Locally Applied Uptake Inhibitors
W. Cass
,
N. Zahniser
,
K. Flach
,
G. Gerhardt
Journal of Neurochemistry
1993
Corpus ID: 24980797
In vivo electrochemistry was used to investigate the mechanisms contributing to the clearance of locally applied dopamine in the…
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Highly Cited
1984
Highly Cited
1984
Platelet phenol sulfotransferase and erythrocyte catechol‐O‐methytransferase activities: Correlation with methyldopa metabolism
N. Campbell
,
J. Dunnette
,
G. Mwaluko
,
J. van Loon
,
R. Weinshilboum
Clinical pharmacology and therapy
1984
Corpus ID: 28982410
Methyldopa is metabolized by sulfate conjugation catalyzed by phenol sulfotransferase (PST), O‐methylation catalyzed by catechol…
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Highly Cited
1970
Highly Cited
1970
Caudate nucleus neurones: correlation of the effects of substantia nigra stimulation with iontophoretic dopamine
J. Connor
Journal of Physiology
1970
Corpus ID: 42558515
1. Extracellular recordings were made from caudate nucleus neurones in decerebrate cats using five‐barrel micropipette electrodes…
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