aldose

 
National Institutes of Health

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Review
2017
Review
2017
Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic complications create a substantial burden on both… (More)
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Highly Cited
2007
Highly Cited
2007
One-pot reactions of aldoses with L-cysteine methyl ester and o-tolyl isothiocyanate yielded methyl 2-(polyhydroxyalkyl)-3-(o… (More)
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Review
2005
Review
2005
Aldose reductase (AR) is widely expressed aldehyde-metabolizing enzyme. The reduction of glucose by the AR-catalyzed polyol… (More)
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Highly Cited
2005
Highly Cited
2005
Direct evidence that hyperglycemia, rather than concomitant increases in known risk factors, induces atherosclerosis is lacking… (More)
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Highly Cited
2005
Highly Cited
2005
In 15-month-old db/db mice, signs of diabetic retinopathy, including blood-retinal barrier breakdown, loss of pericytes, neuro… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Aldose reductase (AR) has been a drug target because of its involvement in the development of secondary complications of… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Analyses in diabetic rats have shown that breakdown of the blood-retina barrier is associated with increased formation of… (More)
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Highly Cited
2003
Highly Cited
2003
The 2-oxoaldehyde methylglyoxal (MeG) is the precursor to a number of the known advanced glycation endproducts (AGE) implicated… (More)
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Highly Cited
1999
Highly Cited
1999
Carbohydrates are major components of marine organic matter, but few molecular-level carbohydrate analyses in seawater have been… (More)
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Highly Cited
1965
Highly Cited
1965
Exposure of the lens of the eye to a high concentration of an aldose, such as n-glucose, n-galactose, or n-xylose, results in the… (More)
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