aldose

 
National Institutes of Health

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AldehydesMonosaccharides

Papers overview

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Review
2017
Review
2017
New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain
Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic complications create a substantial burden on both… (More)
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Highly Cited
2007
Highly Cited
2007
Facile discrimination of aldose enantiomers by reversed-phase HPLC.
One-pot reactions of aldoses with L-cysteine methyl ester and o-tolyl isothiocyanate yielded methyl 2-(polyhydroxyalkyl)-3-(o… (More)
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Review
2005
Review
2005
Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options.
Aldose reductase (AR) is widely expressed aldehyde-metabolizing enzyme. The reduction of glucose by the AR-catalyzed polyol… (More)
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Highly Cited
2005
Highly Cited
2005
Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.
Direct evidence that hyperglycemia, rather than concomitant increases in known risk factors, induces atherosclerosis is lacking… (More)
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Highly Cited
2005
Highly Cited
2005
Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.
In 15-month-old db/db mice, signs of diabetic retinopathy, including blood-retinal barrier breakdown, loss of pericytes, neuro… (More)
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Highly Cited
2004
Highly Cited
2004
Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.
PURPOSE Aldose reductase (AR) has been a drug target because of its involvement in the development of secondary complications of… (More)
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Highly Cited
2003
Highly Cited
2003
High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation.
PURPOSE Analyses in diabetic rats have shown that breakdown of the blood-retina barrier is associated with increased formation of… (More)
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Highly Cited
2003
Highly Cited
2003
Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase.
The 2-oxoaldehyde methylglyoxal (MeG) is the precursor to a number of the known advanced glycation endproducts (AGE) implicated… (More)
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Highly Cited
1999
Highly Cited
1999
Aldoses in various size fractions of marine organic matter : Implications for carbon cycling
Carbohydrates are major components of marine organic matter, but few molecular-level carbohydrate analyses in seawater have been… (More)
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Highly Cited
1965
Highly Cited
1965
ISOLATION AND PROPERTIES OF LENS ALDOSE REDUCTASE.
Exposure of the lens of the eye to a high concentration of an aldose, such as n-glucose, n-galactose, or n-xylose, results in the… (More)
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