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alatrofloxacin

Known as: L-Alaninamide, L-alanyl-N-(3-(6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl)-3-azabicyclo(3.1.0)hex-6-yl)-, (1alpha,5alpha,6alpha)-, alatrofloxacin [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (2)

Alatrofloxacin mesylateCP 116,517

Broader (3)

Anti-Infective AgentsFluoroquinolonesTopoisomerase II Inhibitors
Bacteroides InfectionsBronchitisChlamydia InfectionsDecreased Protein Synthesis [PE]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Thrombocytopenia Associated with Intravenous Ciprofloxacin
A variety of disease states, disorders, hereditary conditions, environmental toxins, and drugs may cause thrombocytopenia… 
2003
2003
Pharmacological evaluation of garenoxacin, a novel des-F(6)-quinolone antimicrobial agent: effects on the central nervous system.
The effects of garenoxacin (formerly T-3811 or BMS-284756) on the central nervous system (CNS) were compared with various… 
2002
2002
Comparison of Levofloxacin, Alatrofloxacin, and Vancomycin for Prophylaxis and Treatment of Experimental Foreign-Body-Associated Infection by Methicillin-Resistant Staphylococcus aureus
ABSTRACT The prophylactic and therapeutic activities of two fluoroquinolones, levofloxacin and alatrofloxacin (the l-Ala-l-Ala… 
2001
2001
Plasma Pharmacokinetics and Tissue Penetration of Alatrofloxacin in Morbidly Obese Individuals
ObjectivesTo characterise the peritoneal and subcutaneous adipose penetration of alatrofloxacin. If the extent of penetration of… 
2000
2000
Pharmacokinetics of a Fluoronaphthyridone, Trovafloxacin (CP 99,219), in Infants and Children following Administration of a Single Intravenous Dose of Alatrofloxacin
ABSTRACT The pharmacokinetics of trovafloxacin following administration of a single intravenous dose of alatrofloxacin… 
1999
1999
A randomized, crossover design study of the pharmacology of extended-spectrum fluoroquinolones for pneumococcal infections.
STUDY OBJECTIVES The objectives of this study were to characterize the single-dose and steady-state plasma pharmacokinetics of IV… 
Review
1999
Review
1999
Chapter 17. New Antibacterials for Resistant Organisms
1998
1998
Safety and tolerability of intravenous-to-oral treatment and single-dose intravenous or oral prophylaxis with trovafloxacin.
1998
1998
Double-blind comparison of single-dose alatrofloxacin and cefotetan as prophylaxis of infection following elective colorectal surgery. Trovafloxacin Surgical Group.
BACKGROUND Alatrofloxacin, the prodrug of trovafloxacin, is a novel fluoroquinolone antimicrobial agent with a broad spectrum… 
1998
1998
Single- and multiple-dose administration, dosing regimens, and pharmacokinetics of trovafloxacin and alatrofloxacin in humans
A simplified dosing algorithm for trovafloxacin was evaluated following a single-dose infusion of alatrofloxacin at trovafloxacin… 
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