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adenophostin A

Known as: 2'-Adenylic acid, 3'-O-(3,4-di-O-phosphono-alpha-D-glucopyranosyl)- 
 
National Institutes of Health

Papers overview

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2003
2003
The synthesis of a series of adenophostin A analogues modified at C-6 and C-2 of adenine is described. The target compounds were… Expand
2002
2002
Inositol 1,4,5-trisphosphate (IP(3)) receptors from cerebellum and recombinant type 1 IP(3) receptors expressed in Sf9 cells had… Expand
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2001
2001
Adenophostin A is the most potent known agonist of inositol 1,4,5-trisphosphate (InsP(3)) receptors. Ca(2+) release from… Expand
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Highly Cited
2000
Highly Cited
2000
Fertilization in mammalian eggs is characterized by the presence of intracellular calcium ([Ca(2+)]i) oscillations. In mouse eggs… Expand
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Highly Cited
2000
Highly Cited
2000
Fertilization in mammals stimulates a series of Ca(2+) oscillations that continue for 3-4 h. Cell-cycle-dependent changes in the… Expand
1999
1999
Mammalian fertilization is characterized by the presence of long-lasting intracellular calcium ([Ca2+]i) oscillations that are… Expand
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1999
1999
Depletion of endoplasmic reticulum Ca2+ stores induces Ca2+ entry from the extracellular space by a process termed “store… Expand
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1999
1999
The recognition mode of adenophostin A at the D-myo-inositol 1,4, 5-trisphosphate [Ins(1,4,5)P(3)] receptor was investigated… Expand
1999
1999
The activation of intracellular calcium release and calcium entry across the plasmalemma in response to intracellular application… Expand
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1997
1997
Adenophostin A possesses the highest known affinity for the inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) receptor (InsP3R). The… Expand