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acyclovir triphosphate

Known as: 9-(2-hydroxyethoxymethyl)guanine triphosphate, triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AcyclovirAntiviral AgentsEnzyme Inhibitors
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Elucidation of functional groups on gram-positive and gram-negative bacterial surfaces using infrared spectroscopy.
Surface functional group chemistry of intact Gram-positive and Gram-negative bacterial cells and their isolated cell walls was… 
Highly Cited
1995
Highly Cited
1995
Famciclovir for the Treatment of Acute Herpes Zoster: Effects on Acute Disease and Postherpetic Neuralgia: A Randomized, Double-Blind, Placebo-Controlled Trial
Herpes zoster (shingles) develops in as many as 20% of all persons [1]. The characteristic zoster rash is often accompanied by… 
Highly Cited
1989
Highly Cited
1989
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.
Acyclovir triphosphate (ACVTP) was a substrate for herpes simplex virus type 1 (HSV-1) DNA polymerase and was rapidly… 
Review
1989
Review
1989
Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.
Acyclovir (aciclovir) is a nucleoside antiviral drug with antiviral activity in vitro against members of the herpes group of DNA… 
Highly Cited
1985
Highly Cited
1985
Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells.
Review
1983
Review
1983
The biochemistry and mechanism of action of acyclovir.
  • G. Elion
  • The Journal of antimicrobial chemotherapy
  • 1983
  • Corpus ID: 29448065
Acyclovir, 9-(2-hydroxyethoxymethyl)guanine, is an acyclic nucleoside analogue which has a high activity and selectivity for… 
Review
1982
Review
1982
Mechanism of action and selectivity of acyclovir.
  • G. Elion
  • The American journal of medicine
  • 1982
  • Corpus ID: 1707773
Highly Cited
1981
Highly Cited
1981
Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function.
Highly Cited
1980
Highly Cited
1980
Acyclovir inhibition of Epstein-Barr virus replication.
Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA… 
1980
1980
The chemotherapeutic exploitation of virus-specified enzymes.
  • G. Elion
  • Advances in enzyme regulation
  • 1980
  • Corpus ID: 20869414
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