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acyclovir triphosphate
Known as:
9-(2-hydroxyethoxymethyl)guanine triphosphate
, triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (3)
Acyclovir
Antiviral Agents
Enzyme Inhibitors
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Elucidation of functional groups on gram-positive and gram-negative bacterial surfaces using infrared spectroscopy.
Wei Jiang
,
A. Saxena
,
B. Song
,
B. Ward
,
T. Beveridge
,
S. Myneni
Langmuir : the ACS journal of surfaces and…
2004
Corpus ID: 25919784
Surface functional group chemistry of intact Gram-positive and Gram-negative bacterial cells and their isolated cell walls was…
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Highly Cited
1995
Highly Cited
1995
Famciclovir for the Treatment of Acute Herpes Zoster: Effects on Acute Disease and Postherpetic Neuralgia: A Randomized, Double-Blind, Placebo-Controlled Trial
S. Tyring
,
R. Barbarash
,
+7 authors
R. Saltzman
Annals of Internal Medicine
1995
Corpus ID: 35498460
Herpes zoster (shingles) develops in as many as 20% of all persons [1]. The characteristic zoster rash is often accompanied by…
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Highly Cited
1989
Highly Cited
1989
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.
J. Reardon
,
T. Spector
The Journal of biological chemistry
1989
Corpus ID: 40440521
Acyclovir triphosphate (ACVTP) was a substrate for herpes simplex virus type 1 (HSV-1) DNA polymerase and was rapidly…
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Review
1989
Review
1989
Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.
J. J. O'Brien
,
D. Campoli-Richards
Drugs
1989
Corpus ID: 195693287
Acyclovir (aciclovir) is a nucleoside antiviral drug with antiviral activity in vitro against members of the herpes group of DNA…
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Highly Cited
1985
Highly Cited
1985
Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells.
D. Smee
,
R. Boehme
,
M. Chernow
,
B. Binko
,
T. Matthews
Biochemical pharmacology
1985
Corpus ID: 32291528
Review
1983
Review
1983
The biochemistry and mechanism of action of acyclovir.
G. Elion
The Journal of antimicrobial chemotherapy
1983
Corpus ID: 29448065
Acyclovir, 9-(2-hydroxyethoxymethyl)guanine, is an acyclic nucleoside analogue which has a high activity and selectivity for…
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Review
1982
Review
1982
Mechanism of action and selectivity of acyclovir.
G. Elion
The American journal of medicine
1982
Corpus ID: 1707773
Highly Cited
1981
Highly Cited
1981
Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function.
D. Derse
,
Y. Cheng
,
P. Furman
,
M. S. St. Clair
,
G. Elion
The Journal of biological chemistry
1981
Corpus ID: 39836150
Highly Cited
1980
Highly Cited
1980
Acyclovir inhibition of Epstein-Barr virus replication.
A. K. Datta
,
B. Colby
,
J. Shaw
,
J. Pagano
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 36522999
Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA…
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1980
1980
The chemotherapeutic exploitation of virus-specified enzymes.
G. Elion
Advances in enzyme regulation
1980
Corpus ID: 20869414
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