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acyclovir triphosphate

Known as: 9-(2-hydroxyethoxymethyl)guanine triphosphate, triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AcyclovirAntiviral AgentsEnzyme Inhibitors
analogs & derivatives

Papers overview

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Highly Cited
2004
Highly Cited
2004
Elucidation of functional groups on gram-positive and gram-negative bacterial surfaces using infrared spectroscopy.
Surface functional group chemistry of intact Gram-positive and Gram-negative bacterial cells and their isolated cell walls was… 
Review
1989
Review
1989
Acyclovir
SummarySynopsisAcyclovir (aciclovir) is a nucleoside antiviral drug with antiviral activity in vitro against members of the… 
Highly Cited
1989
Highly Cited
1989
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.
Acyclovir triphosphate (ACVTP) was a substrate for herpes simplex virus type 1 (HSV-1) DNA polymerase and was rapidly… 
Review
1983
Review
1983
The biochemistry and mechanism of action of acyclovir.
Acyclovir, 9-(2-hydroxyethoxymethyl)guanine, is an acyclic nucleoside analogue which has a high activity and selectivity for… 
Highly Cited
1981
Highly Cited
1981
Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function.
Highly Cited
1981
Highly Cited
1981
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities
The biochemical properties of four acyclovir-resistant mutants are described. Two of these mutants, PAAr5 and BWr, specified… 
Highly Cited
1980
Highly Cited
1980
Acyclovir inhibition of Epstein-Barr virus replication.
Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA… 
Highly Cited
1980
Highly Cited
1980
Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir
The effect of the triphosphate of 9-(2-hydroxyethoxymethyl)guanine (acyclovir, acycloguanosine) on cellular alpha… 
1980
1980
The chemotherapeutic exploitation of virus-specified enzymes.
Highly Cited
1980
Highly Cited
1980
Induction of Epstein-Barr virus-associated DNA polymerase by 12-O-tetradecanoylphorbol-13-acetate. Purification and characterization.
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