FAQ

acyclovir triphosphate

Known as: 9-(2-hydroxyethoxymethyl)guanine triphosphate, triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
012319802017

Related topics

Related topics

3 relations

Broader (3)

AcyclovirAntiviral AgentsEnzyme Inhibitors

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
acyclovir triphosphate
Antiviral Agents
Acyclovir
Enzyme Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation.
The antiviral drug acyclovir is a guanosine nucleoside analog that potently inhibits herpes simplex virus (HSV) replication… (More)
Is this relevant?
1996
1996
Acyclovir triphosphate inhibits the diagnostic polymerase chain reaction for cytomegalovirus.
Immunocompromised patients are frequently treated with guanine analogs such as acyclovir and ganciclovir. Acyclovir triphosphate… (More)
Is this relevant?
1992
1992
Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells.
Expression of the human cytomegalovirus (HCMV) (AD169) DNA polymerase gene under the control of the polyhedrin promoter of… (More)
Is this relevant?
1989
1989
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.
Acyclovir triphosphate (ACVTP) was a substrate for herpes simplex virus type 1 (HSV-1) DNA polymerase and was rapidly… (More)
Is this relevant?
1989
1989
Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition.
The ability of herpes simplex virus type 1 (HSV-1) DNA polymerase, HeLa polymerase alpha, and HeLa polymerase beta to utilize… (More)
  • figure 1
  • table I
  • table 111
  • table 11
  • figure 2
Is this relevant?
1985
1985
Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells.
The antiherpes agent 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) is a much more potent inhibitor of herpes simplex viruses in… (More)
Is this relevant?
1981
1981
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities.
The biochemical properties of four acyclovir-resistant mutants are described. Two of these mutants, PAAr5 and BWr, specified… (More)
Is this relevant?
1981
1981
Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function.
The inhibition of highly purified herpes simplex virus (HSV)-induced and host cell DNA polymerases by the triphosphate form of 9… (More)
Is this relevant?
1980
1980
Acyclovir inhibition of Epstein-Barr virus replication.
Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA… (More)
Is this relevant?
1980
1980
Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir.
The effect of the triphosphate of 9-(2-hydroxyethoxymethyl)guanine (acyclovir, acycloguanosine) on cellular alpha… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?