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Acyclovir

Known as: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, Aciclovir, 9-[(2-Hydroxyethoxy)methyl]guanine 
A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (17)

6-deoxypenciclovir9-(4-hydroxybutyl)guanineAci-SanoraniaAciclovir Alonga
Acyclovir 200 MG Oral CapsuleAcyclovir 200 MG Oral Capsule [Zovirax]Acyclovir 400 MG Oral Tablet [Zovirax]Acyclovir 800 MG Oral Tablet

Papers overview

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Highly Cited
2007
Highly Cited
2007
Early Treatment with Prednisolone or Acyclovir in Bell’s Palsy
BACKGROUND Corticosteroids and antiviral agents are widely used to treat the early stages of idiopathic facial paralysis (i.e… 
Review
2003
Review
2003
Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy
SUMMARY Acyclovir, penciclovir, and their prodrugs have been widely used during the past two decades for the treatment of… 
Highly Cited
2001
Highly Cited
2001
Natural history of neonatal herpes simplex virus infections in the acyclovir era.
OBJECTIVE During the 2 decades in which effective antiviral therapies have been available for neonatal herpes simplex virus (HSV… 
Review
2000
Review
2000
Geometric and electronic structure/function correlations in non-heme iron enzymes.
ion step follows the decarboxylation, which is consistent with the deuterium isotopic effects observed for thymine 7-hydroxylase… 
Highly Cited
1995
Highly Cited
1995
Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral… 
Review
1992
Review
1992
Acyclovir: a decade later.
REPORTS of the clinical efficacy of acyclovir, a selective and specific inhibitor of herpesvirus replication, appeared in the… 
Highly Cited
1989
Highly Cited
1989
Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial.
OBJECTIVE--To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent… 
Highly Cited
1986
Highly Cited
1986
Vidarabine versus acyclovir therapy in herpes simplex encephalitis.
We randomly assigned 208 patients who underwent brain biopsy for presumptive herpes simplex encephalitis to receive either… 
Highly Cited
1977
Highly Cited
1977
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.
A guanine derivative with an acyclic side chain, 2-hydroxyethoxymethyl, at position 9 has potent antiviral activity [dose for 50… 
Highly Cited
1968
Highly Cited
1968
Multiple regression as a general data-analytic system.
Techniques for using multiple regression (MR) as a general variance-accounting procedure of great flexibility, power, and… 
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