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Acyclovir

Known as: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, Aciclovir, 9-[(2-Hydroxyethoxy)methyl]guanine 
A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Corticosteroids and antiviral agents are widely used to treat the early stages of idiopathic facial paralysis (i.e… Expand
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Review
2000
Review
2000
ion step follows the decarboxylation, which is consistent with the deuterium isotopic effects observed for thymine 7-hydroxylase… Expand
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Highly Cited
1995
Highly Cited
1995
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral… Expand
Review
1992
Review
1992
REPORTS of the clinical efficacy of acyclovir, a selective and specific inhibitor of herpesvirus replication, appeared in the… Expand
Highly Cited
1989
Highly Cited
1989
OBJECTIVE--To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent… Expand
Highly Cited
1986
Highly Cited
1986
We randomly assigned 208 patients who underwent brain biopsy for presumptive herpes simplex encephalitis to receive either… Expand
Highly Cited
1984
Highly Cited
1984
One hundred and twenty-seven patients with suspected herpes simplex encephalitis were entered in a randomised, controlled… Expand
Highly Cited
1981
Highly Cited
1981
We conducted a double-blind, placebo-controlled study of acyclovir prophylaxis against infection with herpes simplex virus (HSV… Expand
Highly Cited
1977
Highly Cited
1977
A guanine derivative with an acyclic side chain, 2-hydroxyethoxymethyl, at position 9 has potent antiviral activity [dose for 50… Expand
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Highly Cited
1968
Highly Cited
1968
Techniques for using multiple regression (MR) as a general variance-accounting procedure of great flexibility, power, and… Expand
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