Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,178,546 papers from all fields of science
Search
Sign In
Create Free Account
Acyclovir
Known as:
2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
, Aciclovir
, 9-[(2-Hydroxyethoxy)methyl]guanine
Expand
A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
40 relations
Narrower (17)
6-deoxypenciclovir
9-(4-hydroxybutyl)guanine
Aci-Sanorania
Aciclovir Alonga
Expand
Acyclovir 200 MG Oral Capsule
Acyclovir 200 MG Oral Capsule [Zovirax]
Acyclovir 400 MG Oral Tablet [Zovirax]
Acyclovir 800 MG Oral Tablet
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Early Treatment with Prednisolone or Acyclovir in Bell’s Palsy
Frank M. Sullivan
,
I. Swan
,
+11 authors
F. Daly
New England Journal of Medicine
2007
Corpus ID: 3916563
BACKGROUND Corticosteroids and antiviral agents are widely used to treat the early stages of idiopathic facial paralysis (i.e…
Expand
Review
2003
Review
2003
Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy
T. Bacon
,
M. Levin
,
J. Leary
,
R. Sarisky
,
D. Sutton
Clinical Microbiology Reviews
2003
Corpus ID: 6804933
SUMMARY Acyclovir, penciclovir, and their prodrugs have been widely used during the past two decades for the treatment of…
Expand
Highly Cited
2001
Highly Cited
2001
Natural history of neonatal herpes simplex virus infections in the acyclovir era.
D. Kimberlin
,
C. Y. Lin
,
+17 authors
R. Whitley
Pediatrics
2001
Corpus ID: 38770851
OBJECTIVE During the 2 decades in which effective antiviral therapies have been available for neonatal herpes simplex virus (HSV…
Expand
Review
2000
Review
2000
Geometric and electronic structure/function correlations in non-heme iron enzymes.
E. Solomon
,
T. Brunold
,
+7 authors
J. Zhou
Chemical Reviews
2000
Corpus ID: 38663738
ion step follows the decarboxylation, which is consistent with the deuterium isotopic effects observed for thymine 7-hydroxylase…
Expand
Highly Cited
1995
Highly Cited
1995
Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults
K. Beutner
,
D. Friedman
,
C. Forszpaniak
,
P. Andersen
,
M. Wood
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 25632763
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral…
Expand
Review
1992
Review
1992
Acyclovir: a decade later.
R. Whitley
,
J. W. Gnann
New England Journal of Medicine
1992
Corpus ID: 44452941
REPORTS of the clinical efficacy of acyclovir, a selective and specific inhibitor of herpesvirus replication, appeared in the…
Expand
Highly Cited
1989
Highly Cited
1989
Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial.
D. Rachmilewitz
BMJ
1989
Corpus ID: 2408088
OBJECTIVE--To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent…
Expand
Highly Cited
1986
Highly Cited
1986
Vidarabine versus acyclovir therapy in herpes simplex encephalitis.
R. Whitley
,
C. Alford
,
+6 authors
S. Soong
New England Journal of Medicine
1986
Corpus ID: 25346378
We randomly assigned 208 patients who underwent brain biopsy for presumptive herpes simplex encephalitis to receive either…
Expand
Highly Cited
1977
Highly Cited
1977
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.
G. Elion
,
P. Furman
,
J. A. Fyfe
,
P. D. de Miranda
,
L. Beauchamp
,
H. Schaeffer
Proceedings of the National Academy of Sciences…
1977
Corpus ID: 8613755
A guanine derivative with an acyclic side chain, 2-hydroxyethoxymethyl, at position 9 has potent antiviral activity [dose for 50…
Expand
Highly Cited
1968
Highly Cited
1968
Multiple regression as a general data-analytic system.
Jacob Cohen
1968
Corpus ID: 50278575
Techniques for using multiple regression (MR) as a general variance-accounting procedure of great flexibility, power, and…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE