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Acyclovir

Known as: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, Aciclovir, 9-[(2-Hydroxyethoxy)methyl]guanine 
A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
BACKGROUND The present review is part of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Corticosteroids and antiviral agents are widely used to treat the early stages of idiopathic facial paralysis (i.e… Expand
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE During the 2 decades in which effective antiviral therapies have been available for neonatal herpes simplex virus (HSV… Expand
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Highly Cited
1995
Highly Cited
1995
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral… Expand
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Review
1992
Review
1992
REPORTS of the clinical efficacy of acyclovir, a selective and specific inhibitor of herpesvirus replication, appeared in the… Expand
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Highly Cited
1989
Highly Cited
1989
OBJECTIVE--To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent… Expand
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Highly Cited
1986
Highly Cited
1986
We randomly assigned 208 patients who underwent brain biopsy for presumptive herpes simplex encephalitis to receive either… Expand
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Highly Cited
1981
Highly Cited
1981
We conducted a double-blind, placebo-controlled study of acyclovir prophylaxis against infection with herpes simplex virus (HSV… Expand
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Highly Cited
1977
Highly Cited
1977
A guanine derivative with an acyclic side chain, 2-hydroxyethoxymethyl, at position 9 has potent antiviral activity [dose for 50… Expand
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Highly Cited
1968
Highly Cited
1968
Techniques for using multiple regression (MR) as a general variance-accounting procedure of great flexibility, power, and… Expand
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