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XRCC4 gene

Known as: X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 4, X-ray repair complementing defective repair in Chinese hamster cells 4, X-ray repair, complementing defective, repair in Chinese hamster 
This gene plays a role in the repair of double-strand DNA breaks and V(D)J recombination.
National Institutes of Health

Related topics

Related topics

8 relations
DNA RepairDouble Strand Break RepairNon-Homologous DNA End-JoiningV(D)J Recombination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Corrigendum to: Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
Corrigendum to: Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells In Figure 1 of the… 
2017
2017
Artemis and XRCC4 participate in the DNA damage response to both high- and low-LET radiation in human cell lines
2016
2016
Mitosis-specific phosphorylation of XRCC4 maintains genomic stability by suppression of DSB repair
2015
2015
Mutation s in XRCC4 cause primordial dwarfism without immunodeficiency
2014
2014
Comparison of gene regulatory networks of benign and malignant breast cancer samples with normal samples.
The aim of this study was to explain the pathogenesis and deterioration process of breast cancer. Breast cancer expression… 
2013
2013
Nörofibromatozis Tip 1 Olgularında DNA Tamir Genlerinin Ekspresyonunun Klinik Önemi
Amac: Norofibromatozis Tip 1 (NF1), cesitli fenotiplere sahip, sik gorulen otozomal dominant genetik bir hastaliktir. NF1… 
2010
2010
NHEJ relies on the Ku70-Ku80 complex to recognize DSB’s and recruit other protein factors to the break, including DNA-PKcs and DNA polymerases. These factors allow end processing and yield ends that…
  • 2010
  • Corpus ID: 53069813
Review
2006
Review
2006
Poly ( ADP-RIBOSE ) polymerase-1 ( Parp-1 ) antagonizes topoisomerase I-dependent recombination stimulation by P 53
PARP-1 interacts with and poly(ADP-ribosyl)ates p53 and topoisomerase I, which both participate in DNA recombination. Previously… 
2005
2005
Late radiation morbidity: incidence in a south-east Scottish cohort and investigation into abnormalities in DNA double-strand break repair and damage response
Late normal tissue injury is dose-limiting for radiation therapy of cancer. The molecular mechanisms of this injury are unknown… 
2002
2002
Characterization o f the DNA Ligase IV and XRCC4 complex in the DNA double-strand break repair
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