XPO1 gene

Known as: CRM1, chromosome region maintenance 1 homolog (yeast), Exportin 1 (CRM1 Homolog, Yeast) Gene 
This gene plays a role in the regulation of nuclear export.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
0204019922017

Papers overview

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Review
2015
Review
2015
Nucleocytoplasmic trafficking of proteins/RNAs is essential to normal cellular function. Indeed, accumulating evidence suggests… (More)
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Highly Cited
2014
Highly Cited
2014
We analyzed a large cohort of 1160 untreated CLL patients for novel genetic markers (SF3B1, NOTCH1, FBXW7, MYD88, XPO1) in the… (More)
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Highly Cited
2012
Highly Cited
2012
The nuclear export protein XPO1 is overexpressed in cancer, leading to the cytoplasmic mislocalization of multiple tumor… (More)
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Highly Cited
2011
Highly Cited
2011
Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in adults in Western countries, is a heterogeneous disease with… (More)
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Highly Cited
2008
Highly Cited
2008
The GTPase Ran has a key role in nuclear import and export, mitotic spindle assembly and nuclear envelope formation. The cycling… (More)
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Highly Cited
1999
Highly Cited
1999
The cellular target of leptomycin B (LMB), a nuclear export inhibitor, has been identified as CRM1 (exportin 1), an… (More)
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Highly Cited
1998
Highly Cited
1998
MAP kinase signaling modules serve to transduce extracellular signals to the nucleus of eukaryotic cells, but little is known… (More)
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Highly Cited
1998
Highly Cited
1998
In eukaryotes, mitosis is initiated by M phase promoting factor (MPF), composed of B-type cyclins and their partner protein… (More)
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Highly Cited
1998
Highly Cited
1998
UNLABELLED To study the intracellular localization of MAPKAP kinase 2 (MK2), which carries a putative bipartite nuclear… (More)
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Highly Cited
1997
Highly Cited
1997
Nuclear protein export is mediated by nuclear export signals (NESs), but the mechanisms governing this transport process are not… (More)
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