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X-Linked Combined Immunodeficiency Diseases

Known as: SCID, X Linked, X-SCID, Immunodeficiency Diseases, X-Linked Combined 
Forms of combined immunodeficiency caused by mutations in the gene for INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT. Both severe and non-severe subtypes… 
National Institutes of Health

Related topics

Related topics

24 relations
AgammaglobulinemiaBronchitisCandidal diaper rashChronic diarrhea

Broader (1)

Severe Combined Immunodeficiency

Narrower (1)

Woods Black Norbury syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Immune deficiencies , infection , and systemic immune disorders Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe : Entering a new century…
Andrew R. Gennery, MD,* Mary A. Slatter, MD,* Laure Grandin, MSc, Pierre Taupin, MD, Andrew J. Cant, FRCP, Paul Veys, FRCP… 
Highly Cited
2000
Highly Cited
2000
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
More than 130 different mutations in the gap junction integral plasma membrane protein connexin32 (Cx32) have been linked to the… 
Highly Cited
2000
Highly Cited
2000
Patients with X‐linked lymphoproliferative disease have a defect in 2B4 receptor‐mediated NK cell cytotoxicity
Patients with the X‐linked lymphoproliferative disorder (XLPD) are unable to control Epstein‐Barr virus (EBV)‐induced infections… 
Highly Cited
2000
Highly Cited
2000
Cutting Edge: Defective NK Cell Activation in X-Linked Lymphoproliferative Disease1
X-linked lymphoproliferative disease (XLP) is characterized by a selective immune deficiency to EBV. The molecular basis of XLP… 
Highly Cited
1999
Highly Cited
1999
Cell-Extracellular Matrix Interactions Stimulate the AP-1 Transcription Factor in an Integrin-Linked Kinase- and Glycogen Synthase Kinase 3-Dependent Manner
ABSTRACT Integrin-mediated interactions of cells with components of the extracellular matrix regulate cell survival, cell… 
Highly Cited
1998
Highly Cited
1998
Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex.
Although human immunodeficiency virus (HIV)-infected subjects without acquired immunodeficiency syndrome have a high frequency of… 
Highly Cited
1996
Highly Cited
1996
Interleukin-7 is a critical growth factor in early human T-cell development.
Highly purified human CD34+ fetal liver stem cells differentiate to mature T cells when seeded in vitro into isolated fetal… 
Review
1995
Review
1995
IL‐15, a novel T cell growth factor that shares activities and receptor components with IL‐2
Interleukin 15 is a newly discovered cytokine that shares biological activities with IL‐2 and, like IL‐2, is a member of the four… 
Review
1991
Review
1991
The SCID-hu mouse: a small animal model for HIV infection and pathogenesis.
The SCID-hu mouse is a heterochimeric small animal model designed to support hematopoietic differentiation and function in vivo… 
Review
1982
Review
1982
Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system.
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