WRN protein, human

Known as: Werner Syndrome ATP-Dependent Helicase, RECQ3 protein, human, Werner syndrome helicase, human 
Werner syndrome ATP-dependent helicase (1432 aa, ~162 kDa) is encoded by the human WRN gene. This protein plays a role in both magnesium and ATP… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
02419982016

Papers overview

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2015
2015
Polymorphisms and somatic mutations in Flap Endonuclease 1 (FEN1), an essential enzyme involved in DNA replication and repair… (More)
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2010
2010
BACKGROUND WRN is a multi-functional protein involving DNA replication, recombination and repair. WRN acetylation has been… (More)
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2010
2010
Werner syndrome (WS), caused by mutation of the WRN gene, is an autosomal recessive disorder associated with premature aging and… (More)
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2006
2006
WRN is unique among the five human RecQ DNA helicases in having a functional exonuclease domain (WRN-exo) and being defective in… (More)
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2004
2004
The tumor suppressor protein p53 is emerging as a central regulator of homologous recombination (HR) processes and DNA… (More)
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2004
2004
The Werner syndrome protein, WRN, is a member of the RecQ family of DNA helicases. It possesses both 3'-->5' DNA helicase and 3… (More)
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2002
2002
BLM, WRN, and p53 are involved in the homologous DNA recombination pathway. The DNA structure-specific helicases, BLM and WRN… (More)
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2002
2002
Werner syndrome is a premature aging disorder caused by the lack of an active Werner syndrome protein (WRN). The patients suffer… (More)
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Highly Cited
2001
Highly Cited
2001
Werner syndrome (WS) is a human premature aging disorder characterized by chromosomal instability. The cellular defects of WS… (More)
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2001
2001
DNA replication in higher eukaryotic cells occurs at a large number of discrete sites called replication foci. We have previously… (More)
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