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WRN protein, human

Known as: Werner Syndrome ATP-Dependent Helicase, RECQ3 protein, human, Werner syndrome helicase, human 
Werner syndrome ATP-dependent helicase (1432 aa, ~162 kDa) is encoded by the human WRN gene. This protein plays a role in both magnesium and ATP… 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Werner syndrome protein (WRN) is unusual among RecQ family DNA helicases in having an additional exonuclease activity. WRN is… 
2015
2015
The first step of homology-dependent repair of DNA double-strand breaks (DSBs) is the resection of the 5′ strand to generate 3… 
2014
2014
RecQ C-terminal (RQC) domain is known as the main DNA binding module of RecQ helicases such as Bloom syndrome protein (BLM) and… 
2011
2011
The Werner syndrome protein (WRN) is a nuclear protein with helicase and exonuclease activities, whose loss-of-function mutations… 
2010
2010
Comment on: Li B, et al. Aging 2009; 1:289-302. 
Highly Cited
2009
Highly Cited
2009
Both the Ku subunit of the DNA-dependent protein kinase (DNA-PK) and the facilitator of chromatin transcription (FACT) complex… 
2007
2007
Metal-catalyzed oxidation reactions target amino acids in the metal binding pocket of proteins. Such oxidation reactions… 
Review
2007
Review
2007
Stability of the genome is crucial for survival and faithful transmission of the genetic blueprint to progenitors. During DNA… 
Highly Cited
2003
Highly Cited
2003
ABSTRACT The Werner syndrome protein (WRN) is a caretaker of the human genome, and the Abl kinase is a regulator of the DNA…