Werner Syndrome Helicase

Known as: RECQ3 Protein, Werner Syndrome RecQ-Like Helicase, Werner Syndrome ATP Dependent Helicase 
A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
012319992017

Papers overview

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2017
2017
The structural and biophysical properties typically associated with G-quadruplex (G4) structures render them a significant block… (More)
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2017
2017
The Werner syndrome protein (WRN) suppresses the loss of telomeres replicated by lagging-strand synthesis by a yet to be defined… (More)
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Review
2017
Review
2017
Recent studies show that nuclear RNase P is linked to chromatin structure and function. Thus, variants of this ribonucleoprotein… (More)
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2016
2016
The reactivation of stalled DNA replication via fork regression invokes Holliday junction formation, branch migration, and the… (More)
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2015
2015
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase, WRN. Mice lacking part of… (More)
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2013
2013
Werner syndrome is genetically linked to mutations inWRN that encodes a DNA helicase-nuclease believed to operate at stalled… (More)
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2009
2009
RecQ DNA helicases are critical for preserving genome integrity. Of the five RecQ family members identified in humans, only the… (More)
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Highly Cited
1999
Highly Cited
1999
While all known natural isolates of C. elegans contain multiple copies of the Tc1 transposon, which are active in the soma, Tc1… (More)
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