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BLM gene

Known as: RECQ2, DNA HELICASE, RECQ-LIKE, TYPE 2, RECQ PROTEIN-LIKE 3 
This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
National Institutes of Health

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Related topics

12 relations
BLM protein, humanBloom SyndromeBloom syndrome proteinDNA Repair
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BLM wt Allele

Papers overview

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2016
2016
Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer
BackgroundBloom syndrome is a rare and recessive disorder characterized by loss-of-function mutations of the BLM gene, which… Expand
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Highly Cited
2011
Highly Cited
2011
A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome… Expand
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1999
1999
Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene.
Several eukaryotic homologs of the Escherichia coli RecQ DNA helicase have been found. These include the human BLM gene, whose… Expand
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Review
1985
Review
1985
Evidence for chromosome instability in vivo in bloom syndrome: Increased numbers of micronuclei in exfoliated cells
SummaryThe incidence of exfoliated epithelial cells containing micronuclei was determined in two small human populations, one… Expand
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