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BLM gene
Known as:
RECQ2
, DNA HELICASE, RECQ-LIKE, TYPE 2
, RECQ PROTEIN-LIKE 3
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This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
National Institutes of Health
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Related topics
Related topics
12 relations
BLM protein, human
Bloom Syndrome
Bloom syndrome protein
DNA Repair
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Narrower (1)
BLM wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer
C. Votino
,
C. Laudanna
,
+4 authors
M. Pancione
Journal of Gastroenterology
2016
Corpus ID: 24171000
BackgroundBloom syndrome is a rare and recessive disorder characterized by loss-of-function mutations of the BLM gene, which…
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Highly Cited
2011
Highly Cited
2011
A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
G. Guo
,
Yue Huang
,
Peter Humphreys
,
Xiaozhong Wang
,
Austin G Smith
PloS one
2011
Corpus ID: 1404216
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome…
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Review
2004
Review
2004
Evidence for chromosome instability in vivo in bloom syndrome: Increased numbers of micronuclei in exfoliated cells
M. Rosin
,
J. German
Human Genetics
2004
Corpus ID: 22597999
SummaryThe incidence of exfoliated epithelial cells containing micronuclei was determined in two small human populations, one…
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Highly Cited
1999
Highly Cited
1999
Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene.
K. Kusano
,
M. Berres
,
W. Engels
Genetics
1999
Corpus ID: 12153910
Several eukaryotic homologs of the Escherichia coli RecQ DNA helicase have been found. These include the human BLM gene, whose…
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