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, DNA HELICASE, RECQ-LIKE, TYPE 2
, RECQ PROTEIN-LIKE 3
This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
National Institutes of Health
BLM protein, human
Bloom syndrome protein
BLM wt Allele
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Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer
Journal of Gastroenterology
Corpus ID: 24171000
BackgroundBloom syndrome is a rare and recessive disorder characterized by loss-of-function mutations of the BLM gene, which…
A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
Corpus ID: 1404216
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome…
Evidence for chromosome instability in vivo in bloom syndrome: Increased numbers of micronuclei in exfoliated cells
Corpus ID: 22597999
SummaryThe incidence of exfoliated epithelial cells containing micronuclei was determined in two small human populations, one…
Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene.
Corpus ID: 12153910
Several eukaryotic homologs of the Escherichia coli RecQ DNA helicase have been found. These include the human BLM gene, whose…
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