FAQ

BLM gene

Known as: RECQ2, DNA HELICASE, RECQ-LIKE, TYPE 2, RECQ PROTEIN-LIKE 3 
This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2016
0119852016

Related topics

Related topics

11 relations
BLM protein, humanBloom SyndromeBloom syndrome proteinDNA Repair
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
BLM gene
Genetic Translation Process
DNA Replication
DNA Repair
Recombination, Genetic
RNA Processing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer
Bloom syndrome is a rare and recessive disorder characterized by loss-of-function mutations of the BLM gene, which encodes a RecQ… (More)
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2013
2013
A common nonsense mutation of the BLM gene and prostate cancer risk and survival.
BACKGROUND Germline mutations of BRCA2 and NBS1 genes cause inherited recessive chromosomal instability syndromes and predispose… (More)
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2011
2011
A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome… (More)
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2008
2008
Meiosis genes in Daphnia pulex and the role of parthenogenesis in genome evolution
Thousands of parthenogenetic animal species have been described and cytogenetic manifestations of this reproductive mode are well… (More)
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2006
2006
Enhanced gene targeting efficiency by siRNA that silences the expression of the Bloom syndrome gene in human cells.
Gene targeting via homologous recombination is a powerful tool for studying gene function, but the targeting efficiency in human… (More)
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1999
1999
Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene.
Several eukaryotic homologs of the Escherichia coli RecQ DNA helicase have been found. These include the human BLM gene, whose… (More)
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Review
1985
Review
1985
Evidence for chromosome instability in vivo in bloom syndrome: Increased numbers of micronuclei in exfoliated cells
The incidence of exfoliated epithelial cells containing micronuclei was determined in two small human populations, one homozygous… (More)
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