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Voltage-Gated Sodium Channels

Known as: Voltage-Gated Sodium Channels [Chemical/Ingredient], Sodium Channels, Voltage-Gated, Voltage Gated Sodium Channels 
A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a… 
National Institutes of Health

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Papers overview

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Review
2010
Review
2010
The Tetrodotoxin Receptor of Voltage-Gated Sodium Channels—Perspectives from Interactions with μ-Conotoxins
Neurotoxin receptor site 1, in the outer vestibule of the conducting pore of voltage-gated sodium channels (VGSCs), was first… 
2009
2009
Unexpected synergism between Tetrodotoxin and μ-conotoxin in blocking voltage-gated sodium channels
Tetrodotoxin (TTX) is the quintessential ligand of voltage-gated sodium channels (NaVs). Like TTX, μ-conotoxin peptides are pore… 
Highly Cited
2007
Highly Cited
2007
β-Scorpion Toxin Modifies Gating Transitions in All Four Voltage Sensors of the Sodium Channel
Several naturally occurring polypeptide neurotoxins target specific sites on the voltage-gated sodium channels. Of these, the… 
2007
2007
Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors
2005
2005
Molecular interaction of delta-conotoxins with voltage-gated sodium channels.
Various neurotoxic peptides modulate voltage-gated sodium (Na(V)) channels and thereby affect cellular excitability. Delta… 
Highly Cited
2001
Highly Cited
2001
Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels
Antillatoxin (ATX) is a lipopeptide derived from the pantropical marine cyanobacterium Lyngbya majuscula. ATX is neurotoxic in… 
Highly Cited
2001
Highly Cited
2001
Propofol Blocks Human Skeletal Muscle Sodium Channels in a Voltage-Dependent Manner
Propofol decreases muscle tone in the absence of neuromuscular blocking drugs. This effect probably cannot be attributed solely… 
2000
2000
Diversity of voltage-gated sodium channels in the ascidian larval nervous system.
To gain insight into the origin of the molecular diversity of voltage-gated sodium channels (NaVs), a putative sodium channel… 
Highly Cited
2000
Highly Cited
2000
A role for sodium and chloride in kainic acid-induced beading of inhibitory interneuron dendrites
Highly Cited
1999
Highly Cited
1999
Scorpion α‐like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage‐gated sodium channels in mammals and insects
α‐Like toxins, a unique group designated among the scorpion α‐toxin class that inhibit sodium channel inactivation, are highly… 
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