Skip to search formSkip to main contentSkip to account menu

Vascular Endothelial Growth Factor Receptor-2

Known as: KDR, VEGF Receptor, Fetal Liver Kinase-1, VEGF Receptor Flk 1 
A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their… 
National Institutes of Health

Related topics

Related topics

13 relations
In BloodKDR geneProcess of secretionagonists

Narrower (3)

KDR protein, Coturnix japonicaVascular Endothelial Growth Factor Receptor 2, humankdr protein, zebrafish

Broader (1)

Protein Tyrosine Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability.
Interleukin-8 (IL-8/CXCL8) is a chemokine that increases endothelial permeability during early stages of angiogenesis. However… 
Highly Cited
2007
Highly Cited
2007
Impaired Angiogenesis After Hindlimb Ischemia in Type 2 Diabetes Mellitus: Differential Regulation of Vascular Endothelial Growth Factor Receptor 1 and Soluble Vascular Endothelial Growth Factor…
Deficient angiogenesis after ischemia may contribute to worse outcomes of peripheral arterial disease in patients with diabetes… 
Highly Cited
2006
Highly Cited
2006
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation.
Epidemiological studies have shown that a diet rich in fruits and vegetables has a beneficial preventive effect on cardiovascular… 
Highly Cited
2004
Highly Cited
2004
Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma
The vascular endothelial growth factor (VEGF) family and VEGF receptors (VEGFR) play an essential role in the angiogenesis of… 
Highly Cited
2004
Highly Cited
2004
Grb10 Prevents Nedd4-mediated Vascular Endothelial Growth Factor Receptor-2 Degradation*
One of the cellular mechanisms used to prevent continuous and enhanced activation in response to growth factors is the… 
Highly Cited
2002
Highly Cited
2002
Reactive Oxygen Species as Downstream Mediators of Angiogenic Signaling by Vascular Endothelial Growth Factor Receptor-2/KDR*
Recent evidence shows the involvement of reactive oxygen species (ROS) in the mitogenic cascade initiated by the tyrosine kinase… 
Highly Cited
2001
Highly Cited
2001
Tyrosine Residues 951 and 1059 of Vascular Endothelial Growth Factor Receptor-2 (KDR) Are Essential for Vascular Permeability Factor/Vascular Endothelial Growth Factor-induced Endothelium Migration…
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) exerts its multiple functions by activating two… 
Review
2000
Review
2000
Regulation of angiogenesis via vascular endothelial growth factor receptors.
Endothelial cell signal transduction mechanisms involved in angiogenesis have come into focus in cancer research when it was… 
Highly Cited
1998
Highly Cited
1998
A Recombinant Mutant Vascular Endothelial Growth Factor-C that Has Lost Vascular Endothelial Growth Factor Receptor-2 Binding, Activation, and Vascular Permeability Activities*
The vascular endothelial growth factor (VEGF) and the VEGF-C promote growth of blood vessels and lymphatic vessels, respectively… 
Highly Cited
1995
Highly Cited
1995
Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo.
Vasculogenesis, the de novo formation of embryonic blood vessels from their angioblastic precursors in situ, is supposed to be… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)