Vascular Endothelial Growth Factor Receptor-2

Known as: KDR, VEGF Receptor, Fetal Liver Kinase-1, VEGF Receptor Flk 1 
A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The blood and lymphatic vessel networks are jointly essential for development, wound healing and immune surveillance and… (More)
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Review
2007
Review
2007
Vascular endothelial growth factors (VEGFs) regulate vascular development, angiogenesis and lymphangiogenesis by binding to a… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Given the complex tumor microenvironment, targeting multiple cellular components may be the most effective cancer… (More)
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Highly Cited
2005
Highly Cited
2005
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize… (More)
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Highly Cited
2003
Highly Cited
2003
The stimulation of vascular endothelial growth factor receptor-2 (VEGFR-2) by tumor-derived VEGF represents a key event in the… (More)
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Highly Cited
2002
Highly Cited
2002
Recent evidence shows the involvement of reactive oxygen species (ROS) in the mitogenic cascade initiated by the tyrosine kinase… (More)
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Review
2001
Review
2001
Vascular endothelial growth factor (VEGF) is a secreted mitogen highly specific for cultured endothelial cells. In vivo VEGF… (More)
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Highly Cited
1999
Highly Cited
1999
Interaction between integrin alphavbeta3 and extracellular matrix is crucial for endothelial cells sprouting from capillaries and… (More)
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Highly Cited
1998
Highly Cited
1998
We have identified a member of the VEGF family by computer-based homology searching and have designated it VEGF-D. VEGF-D is most… (More)
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Highly Cited
1992
Highly Cited
1992
Vascular endothelial cell growth factor (VEGF), also known as vascular permeability factor, is an endothelial cell mitogen which… (More)
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