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Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers
The work of liver stem cell biologists, largely carried out in rodent models, has now started to manifest in human investigations and applications. We can now recognize complex regenerative processesExpand
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Report of the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan †
  • I. Ikai, S. Arii, +9 authors M. Kudo
  • Medicine
  • Hepatology research : the official journal of the…
  • 1 September 2007
In the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan, 18 213 individuals were newly registered as patients with primary liver cancer at 645 medical institutions over a period of 2Expand
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Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients.
BACKGROUND & AIMS To elucidate the survival of the patients with unresectable hepatocellular carcinoma (HCC) who underwent transcatheter arterial lipiodol chemoembolization (TACE) and to analyze theExpand
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Expression of vascular endothelial growth factor in human hepatocellular carcinoma
Vascular endothelial growth factor (VEGF) is thought to take an important role in tumor angiogenesis. The present study examined VEGF expression immunohistochemically in hepatocellular carcinomasExpand
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Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin
Cholangiolocellular carcinoma (CLC), a subtype of cholangiocellular carcinoma (CC), is thought to originate from the ductules/canals of Hering, where hepatic progenitor cells (HPCs) are located. WeExpand
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Reevaluation of prognostic factors for survival after liver resection in patients with hepatocellular carcinoma in a Japanese nationwide survey
Advances in the diagnosis and surgical treatment of hepatocellular carcinoma (HCC) have improved the prognosis for patients with HCC who undergo liver resection. The objective of this study was toExpand
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Pathology of hepatocellular carcinoma in Japan: 232 consecutive cases autopsied in ten years
The pathologic findings of 232 consecutive cases of hepatocellular carcinoma (HCC) autopsied during the past ten years at Kurume, Japan, were analyzed from the point of view of global epidemiology,Expand
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Expression of cyclooxygenase‐2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation
Cyclooxygenase (rlCOX) is a key enzyme in the synthesis of prostanoids. Two isoforms of this enzyme have been identified: COX‐1 and COX‐2. Recent studies have suggested that COX‐2, but not COX‐1, mayExpand
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Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids.
In this study, we have investigated the underlying molecular mechanism for the potent proapoptotic effect of luteolin on human hepatoma cells both in vitro and in vivo, focusing on the signalExpand
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Management of Hepatocellular Carcinoma in Japan: Consensus-Based Clinical Practice Guidelines Proposed by the Japan Society of Hepatology (JSH) 2010 Updated Version
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death not only in Japan but also worldwide. Clinical practice guidelines for HCC were first published in 2001 by the EuropeanExpand
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