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Vascular Endothelial Growth Factor Receptor 2, human

Known as: EC 2.7.1.112, vascular endothelial growth factor receptor-2, human, VEGFR2 protein, human 
Vascular endothelial growth factor receptor 2 (1356 aa, ~152 kDa) is encoded by the human KDR gene. This protein is involved in ligand-dependent… Expand
National Institutes of Health

Papers overview

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Review
2004
Review
2004
  • N. Ferrara
  • Endocrine reviews
  • 2004
  • Corpus ID: 37464420
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and an angiogenic inducer in a variety… Expand
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Highly Cited
2003
Highly Cited
2003
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising… Expand
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Highly Cited
1999
Highly Cited
1999
Circulating endothelial progenitor cells (EPCs) have been isolated in peripheral blood of adult species. To determine the origin… Expand
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Review
1997
Review
1997
I. Introduction II. Biological Activities of VEGF III. Organization of the VEGF Gene IV. Properties of the VEGF Isoforms V… Expand
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Highly Cited
1996
Highly Cited
1996
THE endothelial cell-specific vascular endothelial growth factor (VEGF)1–5 and its cellular receptors Flt-1 (refs 6,7) and Flk-1… Expand
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Highly Cited
1996
Highly Cited
1996
Angiogenesis, the sprouting of new blood vessels from pre‐existing ones, and the permeability of blood vessels are regulated by… Expand
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Highly Cited
1996
Highly Cited
1996
ANGIOGENESIS is required for a wide variety of physiological and pathological processes1. The endothelial cell-specific mitogen… Expand
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Highly Cited
1995
Highly Cited
1995
THE receptor tyrosine kinase Flk-1 (ref. 1) is believed to play a pivotal role in endothelial development. Expression of the Flk… Expand
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Highly Cited
1995
Highly Cited
1995
THE vascular endothelial growth factor (VEGF) and its high-affinity binding receptors, the tyrosine kinases Flt-1 and Flk-1, are… Expand
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Highly Cited
1994
Highly Cited
1994
The recently identified placenta growth factor (PIGF) is a member of the vascular endothelial growth factor (VEGF) family of… Expand
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