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Vascular Endothelial Growth Factor Receptor 2, human

Known as: EC 2.7.1.112, vascular endothelial growth factor receptor-2, human, VEGFR2 protein, human 
Vascular endothelial growth factor receptor 2 (1356 aa, ~152 kDa) is encoded by the human KDR gene. This protein is involved in ligand-dependent… 
National Institutes of Health

Related topics

Related topics

46 relations
AE-941Angiogenesis PathwayAngiogenic ProcessCediranib Maleate

Broader (2)

Protein Tyrosine KinaseVascular Endothelial Growth Factor Receptor-2

Papers overview

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2014
2014
A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment
Critical limb ischaemia is the most severe clinical manifestation of peripheral arterial disease. The circulating endothelial… 
2013
2013
Exploring novel KDR inhibitors based on pharmaco-informatics methodology
Abstract Kinase-insert domain-containing receptor (KDR) is one of the important mediators of Vascular endothelial growth factor… 
2009
2009
Vascular endothelial growth factor receptor 2 is a significant negative prognostic biomarker in triple-negative breast cancer: results from a controlled randomised trial of premenopausal breast…
CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts Abstract #1087 Background: Triple-negative breast cancer (TNB… 
2008
2008
Spontaneous myogenic differentiation of Flk-1-positive cells from adult pancreas and other nonmuscle tissues.
At the embryonic or fetal stages, autonomously myogenic cells (AMCs), i.e., cells able to spontaneously differentiate into… 
2007
2007
Dynamics of knockdown pyrethroid insecticide resistance alleles in a field population of Anopheles gambiae s . s . in southwestern Nigeria
Background & objectives: Pyrethroid insecticide resistance in the malaria vector Anopheles gambiae Giles is mainly associated… 
2004
2004
Expression of vascular endothelial growth factor and receptor flk-1 in colon cancer liver metastases
Colorectal carcinoma is the third-leading cause of cancer deaths in the United States. Up to 60% of patients with colon cancer… 
2003
2003
Molecular therapeutics: is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs?
Two manuscripts from the same group in this issue illustrateimportant aspects relevant to the discovery and development of… 
2001
2001
KDR promoter can transcriptionally target cytosine deaminase suicide gene to cancer cells of nonendothelial origin.
The KDR/flk-1 gene promoter is considered to be endothelial cell-specific. We show its activity in two cancer cell lines of non… 
2000
2000
SU 6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors 1
Vascular endothelial growth factor, fibroblast growth factor (FGF), and platelet-derived growth factor (PDGF) and their cognate… 
1986
1986
Effect of method of application on resistance to pyrethroid insecticides in Blattella germanica (Orthoptera: Blattellidae).
A DDT-resistant ( kdr ) strain of Blattella germanica (L.) (VPIDLS) showed broad cross-resistance to all pyrethroids when tested…