Vascular Endothelial Growth Factor Receptor 2, human

Known as: EC 2.7.1.112, vascular endothelial growth factor receptor-2, human, VEGFR2 protein, human 
Vascular endothelial growth factor receptor 2 (1356 aa, ~152 kDa) is encoded by the human KDR gene. This protein is involved in ligand-dependent… (More)
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Vascular endothelial growth factor (VEGF)-A, a major regulator for angiogenesis, binds and activates two tyrosine kinase… (More)
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Review
2004
Review
2004
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and an angiogenic inducer in a variety… (More)
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Highly Cited
2004
Highly Cited
2004
Elevated interstitial fluid pressure, a hallmark of solid tumors, can compromise the delivery of therapeutics to tumors. Here we… (More)
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Highly Cited
2003
Highly Cited
2003
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising… (More)
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Highly Cited
2002
Highly Cited
2002
ZD6474 [N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine]is a potent, p.o. active, low… (More)
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Highly Cited
2001
Highly Cited
2001
Emphysema due to cigarette smoking is characterized by a loss of alveolar structures. We hypothesize that the disappearance of… (More)
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Highly Cited
1998
Highly Cited
1998
Vascular endothelial growth factor (VEGF), a major regulator of angiogenesis, binds to two receptor tyrosine kinases, KDR/Flk-1… (More)
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Highly Cited
1995
Highly Cited
1995
We studied the correlation between expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF… (More)
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Highly Cited
1995
Highly Cited
1995
We have studied the role of the hypoxia-inducible angiogenic growth factor vascular endothelial growth factor (VEGF) in the… (More)
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Highly Cited
1994
Highly Cited
1994
Vascular endothelial growth factor (VEGF) is a homodimeric peptide growth factor which binds to two structurally related tyrosine… (More)
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