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VLDLR protein, human

Known as: VLDL Receptor, Very Low-Density Lipoprotein Receptor, very low density lipoprotein receptor, human 
Very low-density lipoprotein receptor (873 aa, ~96 kDa) is encoded by the human VLDLR gene. This protein plays a role in the modulation of both… 
National Institutes of Health

Related topics

Related topics

16 relations
Cholesterol HomeostasisEGF-Like DomainIntegral Membrane ProteinsLIS1 Pathway

Broader (1)

VLDL receptor

Papers overview

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Highly Cited
2013
Highly Cited
2013
Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low‐density lipoprotein receptor
Recent evidence suggests that obese animals exhibit increased endoplasmic reticulum (ER) stress in the liver and adipose tissue… 
Review
2007
Review
2007
The LDL receptor‐related protein (LRP) family: An old family of proteins with new physiological functions
The low‐density lipoprotein (LDL) receptor is the founding member of a family of seven structurally closely related transmembrane… 
Highly Cited
2005
Highly Cited
2005
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor Published, JLR Papers in Press, May 1, 2005. DOI 10.1194/jlr.M500114-JLR200
Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction with members of the LDL receptor family. ApoE… 
Highly Cited
2004
Highly Cited
2004
X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein
Although many viral receptors have been identified, the ways in which they interact with their cognate viruses are not understood… 
Highly Cited
1998
Highly Cited
1998
Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions: marked induction of scavenger receptor and VLDL receptor expression…
BACKGROUND Atherosclerotic lesions contain foam cells that arise from monocyte-macrophages and smooth muscle cells (SMCs) by… 
Highly Cited
1997
Highly Cited
1997
Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population
Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity… 
Highly Cited
1996
Highly Cited
1996
Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus–mediated transfer of the VLDL receptor gene
Liver directed gene transfer with adenoviral vectors is being considered for the treatment of several metabolic diseases… 
Highly Cited
1996
Highly Cited
1996
VLDL receptor mediates the uptake of human chylomicron remnants in vitro.
The VLDL receptor has been described as a new member of the LDL receptor supergene family that specifically binds VLDL in vitro… 
Highly Cited
1995
Highly Cited
1995
Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.
The low-density lipoprotein (LDL) receptor plays a central role in mammalian cholesterol metabolism, clearing lipoproteins which… 
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