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VE 465

Known as: VE-465 
National Institutes of Health

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VX680

Papers overview

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2011
2011
Vincristine potentiates the anti-proliferative effect of an aurora kinase inhibitor, VE-465, in myeloid leukemia cells.
2010
2010
Response of experimental malignant melanoma models to the pan‐Aurora kinase inhibitor VE‐465
Abstract:  Aurora kinases represent promising novel cancer therapy targets. Genomic analyses of human cutaneous melanoma (CMM… 
2010
2010
Abstract A37: Efficacy of combining a novel Aurora kinase inhibitor with radiotherapy in orthotopic liver tumor model of hepatocellular carcinoma
Radiotherapy is one of the treatment options for hepatocellular carcinoma (HCC), but the unsatisfactory results are mainly due to… 
2009
2009
Vincristine Potentiates the Anti-Leukemia Effect of the Aurora Kinase Inhibitor VE-465 by Enhancing Apoptosis in Myeloid Leukemia Cells.
Abstract 2762 Poster Board II-738 Introduction: Aurora kinases (Aurora-A, Aurora-B, Aurora-C) play an essential role in the… 
2006
2006
Activity of a Novel Aurora Kinase Inhibitor, VE-465, Against T315I Mutant Form of BCR-ABL: In Vitro and In Vivo Studies.
Mutation in the ABL kinase domain is the principal mechanism of imatinib resistance in patients with BCR-ABL-positive leukemia… 
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