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V-165 compound

National Institutes of Health

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Broader (2)

PyransPyrimidines

Papers overview

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2007
2007
Selection of human immunodeficiency virus type 1 resistance against the pyranodipyrimidine V-165 points to a multimodal mechanism of action.
OBJECTIVES We have previously identified the pyranodipyrimidines (PDPs) as a new class of integrase (IN) inhibitors. The most… 
2005
2005
The V165I and T206S/S230N mutations in Human Immunodeficiency Virus-1 integrase confer resistance to the pyranodipyrimidine V-165 and reduce replication capacity
Highly Cited
2004
Highly Cited
2004
Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360
Objectives: Study of HIV-1 resistance development to the diketo analogue S-1360, the first HIV-1 integrase strand transfer… 
2004
2004
ANTI-HIV CHEMOTHERAPY: CURRENT STATE OF THE ART
In recent years, significant progress has been made towards the chemotherapy (and ?prophylaxis) of HIV infections. This progress… 
2004
2004
Multiple Mutations in Human Immunodeficiency Virus-1 Integrase Confer Resistance to the Pyranodipyrimidine V-165
1999
1999
V-165 遊走脾に対する腹腔鏡下脾固定術
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