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UDP-glucuronosyltransferases (UGTs) are essential drug-conjugation enzymes that metabolize a variety of endobiotic and xenobiotic… Expand AIM
This study aimed to investigate the role of miRNAs in UGT1A regulation.
MATERIALS & METHODS
Based on bioinformatic… Expand AimsIndividuals with type 2 diabetes have an increased risk of developing non-alcoholic fatty liver disease (NAFLD), and NAFLD… Expand BACKGROUND & AIMS
Gender influences incidence, progression, and therapy of hepatogastrointestinal diseases. The aim of this study… Expand PurposeIrinotecan (CPT-11) is widely used for the treatment of patients with colorectal cancer. However, the adverse effects… Expand Flavonoids have poor bioavailabilities largely because of metabolism via UDP-glucuronosyltransferases (UGTs). This study aims to… Expand BACKGROUND
The rationale for this study was to assess the expression, activity and localization of the enzymes uridine… Expand Treatment of rats with the microsomal enzyme inducers pregnenolone-16 -carbonitrile (PCN), 3-methylcholanthrene (3-MC), and… Expand The molecular basis for the considerable variation of serum bilirubin levels and the incidence of gallstone formation in patients… Expand