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UGT1A1 protein, human

Known as: UDPGT 1-1, UDP glycosyltransferase 1 family, polypeptide A1, human, UDP-Glucuronosyltransferase 1-1 
UDP-glucuronosyltransferase 1-1 (533 aa, ~60 kDa) is encoded by the human UGT1A1 gene. This protein is involved in the glucuronidation of bilirubin… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
The uridine diphosphate glucuronosyltransferase (UGT) enzymes are a superfamily of enzymes responsible for the glucuronidation of… Expand
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Highly Cited
2008
Highly Cited
2008
UDP-glucuronosyltransferases (UGTs) are major phase II drug metabolism enzymes that catalyze the glucuronidation of numerous… Expand
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Highly Cited
2007
Highly Cited
2007
The formation of beta-D-glucopyranosides (glucuronides) by the UDP-glucuronosyltransferases (UGTs) is a significant metabolic… Expand
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2007
2007
Epigallocatechin gallate (EGCG), a key active ingredient in green tea, has many anti-carcinogenic activities. The aim of the… Expand
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2003
2003
OBJECTIVES Retrospective cholecystography studies in adults with hereditary spherocytosis (HS) suggested detectable gallstones in… Expand
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Highly Cited
2002
Highly Cited
2002
7-Ethyl-10-hydroxycamptothecin (SN-38) is the pharmacologically active metabolite of irinotecan, in addition to being responsible… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE Genetic mutations in the uridine diphosphate (UDP)-glucuronosyltransferase 1A (UGT1A) enzyme promoter have been… Expand
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Review
2000
Review
2000
Uridine-diphosphoglucuronate glucuronosyltransferases (UGTs) are a family of enzymes that conjugate various endogenous and… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS The contribution of glucuronidation toward human drug metabolism is carried out by the Super gene family of UDP… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE Gilbert Syndrome (GS), associated with unconjugated hyperbilirubinemia and decreased bilirubin UDP… Expand
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