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Whole genome microarray analysis of C. elegans rrf‐3 and eri‐1 mutants
Microarray Analysis of the Global Alterations in the Gene Expression in the Placentas From Cigarette‐smoking Mothers
It seems that cigarette smoke acts as a hormone disrupter in the placenta through the expression of CYP1A1, and the unaltered expression of phase II enzymes may result in an increase in the levels of active metabolites and elevated oxidative chemical stress in the Placenta and the fetus.
Induction of cAMP response element modulator (CREM) and inducible cAMP early repressor (ICER) expression in rat brain by uncompetitive N-methyl-D-aspartate receptor antagonists.
- M. Storvik, A. Linden, O. Kontkanen, M. Lakso, E. Castrén, G. Wong
- BiologyThe Journal of pharmacology and experimental…
- 1 July 2000
Evidence is provided for the involvement of CREM and ICER family transcription factors in the pharmacologic effects of uncompetitive NMDA receptor antagonists in the neurochemical actions of agents acting through NMDA receptors.
Aflatoxin B1--a potential endocrine disruptor--up-regulates CYP19A1 in JEG-3 cells.
Dexmedetomidine preconditioning ameliorates kidney ischemia-reperfusion injury
- J. Lempiäinen, P. Finckenberg, E. Mervaala
- Biology, MedicinePharmacology research & perspectives
- 22 April 2014
Kidney ischemia‐reperfusion (I/R) injury is a common cause of acute kidney injury. We tested whether dexmedetomidine (Dex), an alpha2 adrenoceptor (α2‐AR) agonist, protects against kidney I/R injury.…
Determination of endocannabinoids in nematodes and human brain tissue by liquid chromatography electrospray ionization tandem mass spectrometry.
Effect of Dietary Calcium and Dairy Proteins on the Adipose Tissue Gene Expression Profile in Diet-Induced Obesity
- T. Pilvi, M. Storvik, M. Louhelainen, S. Merasto, R. Korpela, E. Mervaala
- Medicine, BiologyLifestyle Genomics
- 1 August 2008
Preliminary findings reveal that targets of a high-calcium diet with whey protein include genes for Adrb3 and leptin, and help to explain how the intake of dairy products might attenuate obesity.
Caenorhabditis Elegans Mutants Predict Regulation of Fatty Acids and Endocannabinoids by the CYP-35A Gene Family
- Vuokko Aarnio, M. Lehtonen, M. Storvik, J. Callaway, M. Lakso, G. Wong
- Biology, MedicineFront. Pharmacol.
- 19 January 2011
A dynamic role for CYP-35A subfamily members in maintaining the diversity of fatty acid profiles in C. elegans is demonstrated, and the importance of CYPs in generating both structural and signaling fatty acid functions in other organisms is highlighted.
The Association of Ambient Temperature and Violent Crime
- J. Tiihonen, P. Halonen, Laura Tiihonen, H. Kautiainen, M. Storvik, J. Callaway
- PsychologyScientific Reports
- 28 July 2017
The results suggest that the effect of ambient temperature on occurrence of violent crime is partly mediated through the serotonergic system, and that a 2 °C increase in average temperatures would increase violent crime rates by more than 3% in non-tropical and non-subtropical areas, if other contributing factors remained constant.
Lower serotonin transporter binding in caudate in alcoholics
Preliminary evidence is given to suggest that the SERT binding in the dorsal striatum may be lower in alcoholics, and that the serotonergic system may be affected in cortical and striatal areas simultaneously.