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Type 1 Regulatory T-Cell

Known as: Type 1 Regulatory T Cell, Type 1 Regulatory T-Lymphocyte, Tr1 Cell 
A population of CD4+, CD25-, and FoxP3- T-lymphocytes that are involved in immunotolerance. These cells secrete the immunosuppressive cytokines… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Hematopoietic and Lymphoid TissueLymphoid TissueTr1 Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk
Investigation of host-environment interactions in the gut would benefit from a culture system that maintained tissue architecture… Expand
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Highly Cited
2015
Highly Cited
2015
Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10–Dependent Mechanism
The two best-characterized types of CD4+ regulatory T cells (Tregs) are Foxp3+ Tregs and Foxp3− type 1 regulatory (Tr1) cells… Expand
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2012
2012
Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells.
Type 1 regulatory T (Tr1) cells are an inducible subset of CD4(+) Tr cells characterized by high levels of interleukin (IL)-10… Expand
Review
2007
Review
2007
IL-10-producing type 1 regulatory T cells and allergy.
As an important subset of regulatory T (Treg) cells, IL-10-producing type 1 regulatory T cells (Tr1), have some different… Expand
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Highly Cited
2006
Highly Cited
2006
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse.
To identify interleukin-10 (IL-10)-producing cells in vivo, we generated a knockin mouse where an internal ribosome entry site… Expand
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Review
2006
Review
2006
Regulatory T cells and transplantation tolerance.
In the past decade, several types of regulatory T cells (Tregs) have been identified to play a pivotal role in the control of… Expand
Highly Cited
2003
Highly Cited
2003
Type 1 T-regulatory cells: their role in the control of immune responses1
  • H. Groux
  • Transplantation
  • 2003
    • Corpus ID: 35915386
The induction of tolerance is essential for the maintenance of immune homeostasis, for the prevention of autoimmune diseases, and… Expand
Review
2002
Review
2002
The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells
Suppression by T regulatory (Tr) cells is essential for the induction of peripheral tolerance. Many types of CD4+ Tr cells have… Expand
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Review
2001
Review
2001
Type 1 T regulatory cells
Summary: Suppression by T regulatory (Tr) cells is essential for induction of tolerance. Many types of Tr cells have been… Expand
Highly Cited
2001
Highly Cited
2001
Heterogeneity within Animal Thioredoxin Reductases
Animal thioredoxin reductases (TRs) are selenocysteine-containing flavoenzymes that utilize NADPH for reduction of thioredoxins… Expand
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