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Type 1 Regulatory T-Cell

Known as: Type 1 Regulatory T Cell, Type 1 Regulatory T-Lymphocyte, Tr1 Cell 
A population of CD4+, CD25-, and FoxP3- T-lymphocytes that are involved in immunotolerance. These cells secrete the immunosuppressive cytokines… 
National Institutes of Health

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Hematopoietic and Lymphoid TissueLymphoid TissueTr1 Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Helios+ and Helios− Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
The transcription factor Helios is expressed in a large subset of Foxp3+ Tregs. We previously proposed that Helios is a marker of… 
Review
2015
Review
2015
Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance
The lack of immune response to an antigen, a process known as immune tolerance, is essential for the preservation of immune… 
Highly Cited
2013
Highly Cited
2013
A-Type Proanthocyanidins from the Stems of Ephedra sinica (Ephedraceae) and Their Antimicrobial Activities
Phytochemical investigation of the n-BuOH-soluble fraction of the EtOH extract of the herbaceous stems of Ephedra sinica, which… 
Highly Cited
2012
Highly Cited
2012
Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells.
Type 1 regulatory T (Tr1) cells are an inducible subset of CD4(+) Tr cells characterized by high levels of interleukin (IL)-10… 
Highly Cited
2012
Highly Cited
2012
Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice.
Although cancer tends to affect the elderly, most preclinical studies are carried out in young subjects. In this study, we… 
2009
2009
Clinical grade production of IL-10 producing regulatory Tr1 lymphocytes for cell therapy of chronic inflammatory diseases.
Review
2007
Review
2007
IL-10-producing type 1 regulatory T cells and allergy.
As an important subset of regulatory T (Treg) cells, IL-10-producing type 1 regulatory T cells (Tr1), have some different… 
Review
2006
Review
2006
Regulatory T cells and transplantation tolerance.
Highly Cited
2003
Highly Cited
2003
Type 1 T-regulatory cells: their role in the control of immune responses1
The induction of tolerance is essential for the maintenance of immune homeostasis, for the prevention of autoimmune diseases, and… 
Highly Cited
2003
Highly Cited
2003
Mechanisms of Variable p44 Expression by Anaplasma phagocytophilum
ABSTRACT The human intragranulocytic bacterium Anaplasma phagocytophilum promotes variation of P44s, which are surface-exposed… 
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