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Chemical Constituents from the Rhizomes of Smilax glabra and Their Antimicrobial Activity
TLDR
The results indicated that these antimicrobial constituents of this crude drug might be responsible for its clinical antimicrobial effect.
Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn
TLDR
This is the first report of the in vivo biotransformation of a single compound into more than 100 metabolites and indicates that taxifolin is bioactive not only in the parent form, but also through its metabolites.
Trollioside, a new compound from the flowers of Trollius chinensis
A new compound, named trollioside, together with nine known compounds, proglobeflowery acid, isoswertisin, isoswertiajaponin, cirsimaritin, veratric acid, vitexin, orientin, β-sitosterol and
The profiling and identification of the absorbed constituents and metabolites of Paeoniae Radix Rubra decoction in rat plasma and urine by the HPLC-DAD-ESI-IT-TOF-MS(n) technique: a novel strategy
  • Jing Liang, F. Xu, +8 authors S. Cai
  • Chemistry, Medicine
    Journal of pharmaceutical and biomedical analysis
  • 1 September 2013
TLDR
This study is the first to explore the absorption and metabolism of PRR decoction, and the result also is a notable improvement in the discovery of paeoniflorin metabolites in vivo.
ABSORPTION AND METABOLISM OF ASTRAGALI RADIX DECOCTION: IN SILICO, IN VITRO, AND A CASE STUDY IN VIVO
TLDR
It is demonstrated that the flavonoids in Astragali Radix decoction, including is oflavones, pterocarpans, and isoflavans, could be absorbed and metabolized by the intestine during absorption.
Comparative analysis of two species of Asari Radix et Rhizoma by electronic nose, headspace GC-MS and chemometrics.
  • Chen Li, F. Xu, +6 authors S. Cai
  • Chemistry, Medicine
    Journal of pharmaceutical and biomedical analysis
  • 1 November 2013
TLDR
Electronic nose, headspace gas chromatography-mass spectrometry (GC-MS) and chemometrics methods were applied and can successfully differentiate two species of Asari Radix et Rhizoma by their odors.
Aristololactams and aporphines from the stems of Fissistigma oldhamii (Annonaceae).
TLDR
The results demonstrated that the CHCl(3)-soluble part and alkaloid 2 exhibited significant anti-inflammatory activity in vitro in both assays.
A-Type Proanthocyanidins from the Stems of Ephedra sinica (Ephedraceae) and Their Antimicrobial Activities
TLDR
Phytochemical investigation of the n-BuOH-soluble fraction of the EtOH extract of the herbaceous stems of Ephedra sinica led to the isolation and identification of 12 A-type proanthocyanidins, containing five dimers, two trimers and five tetramers.
The profiling and identification of the metabolites of (+)-catechin and study on their distribution in rats by HPLC-DAD-ESI-IT-TOF-MS(n) technique.
TLDR
The in vivo metabolic reactions of (+)-catechin in rats were found to be ring-cleavage, sulfation, glucuronidation, methylation, dehydroxylation and dehydrogenation, and it was indicated that small intestine, kidney and liver were the major organs for the distribution of (+- catechin metabolites.
Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography
TLDR
A fast and economical HPLC method is developed, and applied for the determination of norephedrine, norpseudoephedrin, ephedrine (E), pseudoephedrine(PE) and methylephedrin (ME) in 64 samples of three species from main habitats in China.
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