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Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… Expand
National Institutes of Health

Papers overview

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Highly Cited
1994
Highly Cited
1994
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… Expand
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Review
1992
Review
1992
The therapeutic uses of naturally occurring psoralens in modern-day medicine (8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP… Expand
Highly Cited
1988
Highly Cited
1988
In conditions in which solely monoadducts (MA) are induced in DNA, i.e., treatment with 4,5',8-trimethylpsoralen and 405 nm… Expand
Highly Cited
1988
Highly Cited
1988
Diluted plasma samples containing 10(2), 10(3), 10(4), and 10(5) chimpanzee infectious doses (CID) of a human non-A, non-B… Expand
Highly Cited
1986
Highly Cited
1986
The psoralens, when activated by ultraviolet light of 320-400 nm (UVA light), are potent modulators of epidermal cell growth and… Expand
Highly Cited
1982
Highly Cited
1982
The isolation and structural characterization are described of the major monoaddition products formed in the photoreaction of two… Expand
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Highly Cited
1977
Highly Cited
1977
The synthesis of five new psoralen derivatives is described. Three of these, 4'-hydroxymethyl-4,5',8-trimethylpsoralen, 4… Expand
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Highly Cited
1977
Highly Cited
1977
The furocoumarin, 4,5',8-trimethylpsoralen, sensitizes cells and viruses to 360 nm light, producing cross-links and monoadducts… Expand
Highly Cited
1976
Highly Cited
1976
Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0.5 mg/1) for 15 minutes followed by irradiation with… Expand
Highly Cited
1973
Highly Cited
1973
Abstract Exposure of Chinese hamster cells to near ultraviolet light in the presence of 4,5′,8-trimethylpsoralen (psoralen… Expand