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Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Fanconi anemia (FA) is an inherited cancer-susceptibility disorder, characterized by genomic instability, hypersensitivity to DNA… Expand
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Highly Cited
1999
Highly Cited
1999
It has been suggested that trioxsalen bath and ultraviolet (UV) A (PUVA) is associated with a very low or no risk of non‐melanoma… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Systemic methoxsalen PUVA increases nonmelanoma skin cancer risk in a dose-dependent manner, whereas trioxsalen bath… Expand
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1995
1995
Summary Topical photochemotherapy with psoralen and its derivatives 4.5′,8‐trimethylpsoralen (TMP) and 8‐methoxypsoralen (8‐MOP… Expand
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Highly Cited
1994
Highly Cited
1994
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… Expand
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Review
1992
Review
1992
The therapeutic uses of naturally occurring psoralens in modern-day medicine (8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND AND DESIGN There is an increasing concern about the long-term carcinogenic effect of oral psoralen with long-wave UV… Expand
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Highly Cited
1982
Highly Cited
1982
The isolation and structural characterization are described of the major monoaddition products formed in the photoreaction of two… Expand
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Highly Cited
1977
Highly Cited
1977
The synthesis of five new psoralen derivatives is described. Three of these, 4'-hydroxymethyl-4,5',8-trimethylpsoralen, 4… Expand
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Highly Cited
1976
Highly Cited
1976
Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0.5 mg/1) for 15 minutes followed by irradiation with… Expand
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