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Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… Expand
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (6)

4,8-dimethyl-5'-carboxypsoralenTrisoralenaminomethyltrioxsalenhydroxymethyltrioxsalen
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AlbinismChildDisorders of Porphyrin MetabolismDrug Allergy
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Broader (2)

Photosensitizing AgentsTrimethylpsoralen

Papers overview

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Highly Cited
1994
Highly Cited
1994
Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… Expand
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Review
1992
Review
1992
The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD.
The therapeutic uses of naturally occurring psoralens in modern-day medicine (8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP… Expand
Highly Cited
1988
Highly Cited
1988
Repair of 4,5',8-trimethylpsoralen plus light-induced DNA damage in normal and Fanconi's anemia cell lines.
In conditions in which solely monoadducts (MA) are induced in DNA, i.e., treatment with 4,5',8-trimethylpsoralen and 405 nm… Expand
Highly Cited
1988
Highly Cited
1988
PHOTOCHEMICAL DECONTAMINATION OF BLOOD COMPONENTS CONTAINING HEPATITIS B AND NON-A, NON-B VIRUS
Diluted plasma samples containing 10(2), 10(3), 10(4), and 10(5) chimpanzee infectious doses (CID) of a human non-A, non-B… Expand
Highly Cited
1986
Highly Cited
1986
Psoralens potentiate ultraviolet light-induced inhibition of epidermal growth factor binding.
The psoralens, when activated by ultraviolet light of 320-400 nm (UVA light), are potent modulators of epidermal cell growth and… Expand
Highly Cited
1982
Highly Cited
1982
Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.
The isolation and structural characterization are described of the major monoaddition products formed in the photoreaction of two… Expand
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Highly Cited
1977
Highly Cited
1977
Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA.
The synthesis of five new psoralen derivatives is described. Three of these, 4'-hydroxymethyl-4,5',8-trimethylpsoralen, 4… Expand
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Highly Cited
1977
Highly Cited
1977
Genetic effects of photoadducts and photocross-links in the DNA of phage lambda exposed to 360 nm light and tri-methylpsoralen or khellin.
The furocoumarin, 4,5',8-trimethylpsoralen, sensitizes cells and viruses to 360 nm light, producing cross-links and monoadducts… Expand
Highly Cited
1976
Highly Cited
1976
Treatment of psoriasis with trioxsalen baths and dysprosium lamps.
Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0.5 mg/1) for 15 minutes followed by irradiation with… Expand
Highly Cited
1973
Highly Cited
1973
DNA cross-linking in Chinese hamster cells exposed to near ultraviolet light in the presence of 4,5',8-trimethylpsoralen.
Abstract Exposure of Chinese hamster cells to near ultraviolet light in the presence of 4,5′,8-trimethylpsoralen (psoralen… Expand
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