Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… (More)
National Institutes of Health

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24 relations

Narrower (6)

4,8-dimethyl-5'-carboxypsoralenTrisoralenaminomethyltrioxsalenhydroxymethyltrioxsalen
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AlbinismChildDisorders of Porphyrin MetabolismDrug Allergy
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Broader (2)

Photosensitizing AgentsTrimethylpsoralen

Papers overview

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2007
2007
Psoralen conjugates for visualization of genomic interstrand cross-links localized by laser photoactivation.
DNA interstrand cross-links are formed by chemotherapy drugs as well as by products of normal oxidative metabolism. Despite their… (More)
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2004
2004
Psoralen derivatives and longwave ultraviolet irradiation are active in vitro against human melanoma cell line.
Cutaneous malignant melanoma is a very serious form of skin cancer that arises from melanocytes. Currently there is no effective… (More)
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2000
2000
Arrest of S-phase progression is impaired in Fanconi anemia cells.
Fanconi anemia (FA) is an inherited cancer-susceptibility disorder, characterized by genomic instability, hypersensitivity to DNA… (More)
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Highly Cited
1998
Highly Cited
1998
Nonsurgical repigmentation therapies in vitiligo. Meta-analysis of the literature.
OBJECTIVE To assess the effectiveness and safety of nonsurgical repigmentation therapies in localized and generalized vitiligo by… (More)
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1996
1996
Cancer incidence among Finnish patients with psoriasis treated with trioxsalen bath PUVA.
BACKGROUND Systemic methoxsalen PUVA increases nonmelanoma skin cancer risk in a dose-dependent manner, whereas trioxsalen bath… (More)
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Highly Cited
1994
Highly Cited
1994
Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… (More)
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Review
1992
Review
1992
The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD.
The therapeutic uses of naturally occurring psoralens in modern-day medicine (8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP… (More)
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1981
1981
Long-term local trioxsalen photochemotherapy in psoriasis.
Good results were achieved in psoriasis with trioxsalen baths and UVA in 92% of 158 patients during initial treatment and in 83… (More)
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1978
1978
Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis.
Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light… (More)
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1976
1976
Treatment of psoriasis with trioxsalen baths and dysprosium lamps.
Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0.5 mg/1) for 15 minutes followed by irradiation with… (More)
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