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Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (6)

4,8-dimethyl-5'-carboxypsoralenTrisoralenaminomethyltrioxsalenhydroxymethyltrioxsalen
AlbinismChildDisorders of Porphyrin MetabolismDrug Allergy

Broader (2)

Photosensitizing AgentsTrimethylpsoralen

Papers overview

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Highly Cited
1998
Highly Cited
1998
Nonsurgical repigmentation therapies in vitiligo. Meta-analysis of the literature.
OBJECTIVE To assess the effectiveness and safety of nonsurgical repigmentation therapies in localized and generalized vitiligo by… 
Highly Cited
1997
Highly Cited
1997
Isolation and characterization of CYP6B4, a furanocoumarin-inducible cytochrome P450 from a polyphagous caterpillar (Lepidoptera:papilionidae).
Highly Cited
1994
Highly Cited
1994
Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… 
Review
1992
Review
1992
The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD.
Highly Cited
1992
Highly Cited
1992
Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report.
BACKGROUND AND DESIGN There is an increasing concern about the long-term carcinogenic effect of oral psoralen with long-wave UV… 
Highly Cited
1988
Highly Cited
1988
Repair of 4,5',8-trimethylpsoralen plus light-induced DNA damage in normal and Fanconi's anemia cell lines.
In conditions in which solely monoadducts (MA) are induced in DNA, i.e., treatment with 4,5',8-trimethylpsoralen and 405 nm… 
Highly Cited
1982
Highly Cited
1982
Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.
The isolation and structural characterization are described of the major monoaddition products formed in the photoreaction of two… 
Highly Cited
1977
Highly Cited
1977
Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA.
The synthesis of five new psoralen derivatives is described. Three of these, 4'-hydroxymethyl-4,5',8-trimethylpsoralen, 4… 
Highly Cited
1976
Highly Cited
1976
Treatment of psoriasis with trioxsalen baths and dysprosium lamps.
Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0.5 mg/1) for 15 minutes followed by irradiation with… 
Highly Cited
1973
Highly Cited
1973
DNA cross-linking in Chinese hamster cells exposed to near ultraviolet light in the presence of 4,5',8-trimethylpsoralen.
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