Skip to search formSkip to main contentSkip to account menu

Trioxsalen

Known as: 2',4,8-Trimethylpsoralen, Trioxysalen, Trioxysalene 
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (6)

4,8-dimethyl-5'-carboxypsoralenTrisoralenaminomethyltrioxsalenhydroxymethyltrioxsalen
AlbinismChildDisorders of Porphyrin MetabolismDrug Allergy

Broader (2)

Photosensitizing AgentsTrimethylpsoralen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Photodynamic antisense regulation of human cervical carcinoma cell growth using psoralen-conjugated oligo(nucleoside phosphorothioate).
The antisense strategy has been applied to regulate gene expression in a sequence specific manner, which enables suppression of… 
1988
1988
DNA sequence specificity of 4,5',8-trimethylpsoralen cross-linking. Effect of neighboring bases on cross-linking the 5'-TA dinucleotide.
1987
1987
Reduced 4,5',8-trimethylpsoralen cross-linking of left-handed Z-DNA stabilized by DNA supercoiling.
Z-DNA-forming sequences, (GT)21, (GT)12ATGT, and (CG)6TA(CG)6, were cloned into plasmids. These sequences formed left-handed Z… 
Highly Cited
1985
Highly Cited
1985
Comparison of trioxsalen bath and oral methoxsalen PUVA in psoriasis.
Fifty patients with chronic plaque psoriasis were treated with trioxsalen bath PUVA and 43 patients with oral methoxsalen PUVA… 
1983
1983
Herpes simplex virus types 1 and 2 induce shutoff of host protein synthesis by different mechanisms in Friend erythroleukemia cells
Herpes simplex virus type 1 (HSV-1) and HSV-2 disrupt host protein synthesis after viral infection. We have treated both viral… 
Highly Cited
1978
Highly Cited
1978
Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis
Seventy‐four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 1 of water) and long wave ultraviolet light… 
Highly Cited
1976
Highly Cited
1976
Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences.
It has been suggested that inverted repeat (palindrome) sequences, which are widespread in eukaryotic genomes, exist in two… 
Highly Cited
1973
Highly Cited
1973
DNA cross-linking in Chinese hamster cells exposed to near ultraviolet light in the presence of 4,5',8-trimethylpsoralen.
Highly Cited
1973
Highly Cited
1973
Psoralen plus black light inhibits epidermal DNA synthesis.
Psoralens have been used previously in an attempt to repigment vitiliginous skin. Recent reports indicate psoralens, activated by… 
1970
1970
PHOTOADDITION OF PSORALEN AND OF 4, 5', 8‐TRIMETHYLPSORALEN TO DNA
Recently, we have shown that 4,5', 8-trimethylpsoralen ( 1) undergoes photoaddition to epidermal DNA and epidermal ribosomal RNA… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)