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Trimethylpsoralen

National Institutes of Health

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Trioxsalen

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2001
2001
Concentration‐dependent phototoxicity in trimethylpsoralen bath psoralen ultraviolet A
Background  Long‐term use of topical trimethylpsoralen (TMP) psoralen bath plus ultraviolet A (bath PUVA) is considered safe with… 
1983
1983
Skin photosensitizing and Langerhans' cell depleting activity of topical (bath) PUVA therapy: comparison of trimethylpsoralen and 8-methoxypsoralen.
The skin photosensitizing and Langerhans' cell (LC) depleting effects of a single bath PUVA exposure were studied in 22 healthy… 
1982
1982
New procedure using a psoralen derivative for analysis of nucleosome associated DNA sequences in chromatin of living cells.
Sites for restriction endonuclease cleavage in double helical DNA are blocked from cleavage when the photoaffinity drug… 
1981
1981
Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.
The reaction between RNA and 4'hydroxymethyl-4,5',8-trimethylpsoralen has been studied. Both natural RNA and synthetic RNAs were… 
1980
1980
Effect of UV-B erythema of psoralen, trimethylpsoralen, and 8 methoxypsoralen.
The MED for UV-B was measured 2 h and 24 h after oral intake of Psoralen (P) 0.49 mg/kg in 10 healthy volunteers. MED was… 
1979
1979
Inhibition by trioxalen (psoralen) plus near-ultraviolet light of the induction of ornithine decarboxylase in Chinese-hamster cells.
Trioxalen (trimethylpsoralen) plus near-u.v. light, a potent inhibitor of DNA and RNA synthesis, inhibits the induction of… 
1977
1977
The pigmentary response to photochemotherapy.
Previous studies on skin topically photosensitized with trimethylpsoralen and subsequently irradiated with long-wave UV light… 
Highly Cited
1976
Highly Cited
1976
Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences.
It has been suggested that inverted repeat (palindrome) sequences, which are widespread in eukaryotic genomes, exist in two… 
1976
1976
Oral trimethylpsoralen in the treatment of vitiligo.
One hundred and 18 children with various clinical types of vitiligo, were treated with oral trimethylpsoralen (Trisoralen, P. B… 
1973
1973
Ineffectiveness of trioxsalen as an oral photosensitizer.
The phototoxicity of methoxsalen (8-methoxypsoralen [8-MOP]) and trioxsalen (trimethylpsoralen) has been compared in humans… 
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