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Trimethylpsoralen

 
National Institutes of Health

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Trioxsalen

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Highly Cited
2012
Highly Cited
2012
Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method
BackgroundTransgenic strains of Caenorhabditis elegans are typically generated by injecting DNA into the germline to form multi… Expand
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2004
2004
Randomized half-side comparison of narrowband UVB and trimethylpsoralen bath plus UVA treatments for psoriasis.
The efficacy of trimethylpsoralen bath PUVA and UVB TL01 were compared in chronic plaque psoriasis. Patients were randomly… Expand
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Highly Cited
2000
Highly Cited
2000
Characterization of mutations induced by ethyl methanesulfonate, UV, and trimethylpsoralen in the nematode Caenorhabditis elegans.
The genome project of the nematode Caenorhabditis elegans is completed. It is important and useful to disrupt nematode genes to… Expand
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Highly Cited
1999
Highly Cited
1999
High-throughput isolation of Caenorhabditis elegans deletion mutants.
The nematode Caenorhabditis elegans is the first animal whose genome is completely sequenced, providing a rich source of gene… Expand
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Highly Cited
1994
Highly Cited
1994
Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.
To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc… Expand
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Highly Cited
1990
Highly Cited
1990
mus308 mutants of Drosophila exhibit hypersensitivity to DNA cross-linking agents and are defective in a deoxyribonuclease.
Mutagen-sensitive strains that identify 16 different Drosophila genes have been screened for alterations in DNA metabolic enzymes… Expand
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1981
1981
Alkaline gel electrophoresis of deoxyribonucleic acid photoreacted with trimethylpsoralen: rapid and sensitive detection of interstrand cross-links.
  • T. Cech
  • Biochemistry
  • 1981
    • Corpus ID: 23744407
Restriction fragments of phage lambda and phi X174 deoxyribonucleic acid (DNA) were photoreacted with 4,5',8-trimethylpsoralen to… Expand
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Highly Cited
1980
Highly Cited
1980
Torsional tension in the DNA double helix measured with trimethylpsoralen in living E. coli cells: Analogous measurements in insect and human cells
The rate of covalent photobinding of trimethylpsoralen to DNA is greater when the DNA is wound with negative superhelical tension… Expand
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Highly Cited
1977
Highly Cited
1977
Cross-linking of DNA with trimethylpsoralen is a probe for chromatin structure
Abstract Me 3 -psoralen (4,5′,8-trimethylpsoralen) undergoes a photochemical reaction with DNA, resulting in the formation of… Expand
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1976
1976
Oral trimethylpsoralen in the treatment of vitiligo.
One hundred and 18 children with various clinical types of vitiligo, were treated with oral trimethylpsoralen (Trisoralen, P. B… Expand
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