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Trimethoprim

Known as: Trimetoprima, 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine, Trimethoprimum 
A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial… 
National Institutes of Health

Related topics

Related topics

44 relations
Anemia, MegaloblasticBacterial InfectionsBronchitisEscherichia coli Infections

Broader (3)

Anti-Bacterial AgentsAntimalarialsdiaminopyrimidine

Narrower (17)

BactrimPolymyxin B / TrimethoprimPolytrimPolytrim eyedrops

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Live-cell super-resolution imaging with trimethoprim conjugates
The spatiotemporal resolution of subdiffraction fluorescence imaging has been limited by the difficulty of labeling proteins in… 
Highly Cited
2007
Highly Cited
2007
Distribution of macrolides, sulfonamides, and trimethoprim in tropical waters: ubiquitous occurrence of veterinary antibiotics in the Mekong Delta.
We investigated the distributions of 12 antibiotics (viz., sulfonamides, macrolides, and trimethoprim) in the water from the… 
Review
2006
Review
2006
The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment.
Highly Cited
2006
Highly Cited
2006
Occurrence of antibiotics in hospital, residential, and dairy effluent, municipal wastewater, and the Rio Grande in New Mexico.
Highly Cited
2006
Highly Cited
2006
Enhanced biodegradation of iopromide and trimethoprim in nitrifying activated sludge.
Iopromide (an X-ray contrast agent) and trimethoprim (an antibacterial drug) are frequently detected pharmaceuticals in effluents… 
Highly Cited
2006
Highly Cited
2006
Behavior of fluoroquinolones and trimethoprim during mechanical, chemical, and active sludge treatment of sewage water and digestion of sludge.
The behavior and fate of three fluoroquinolones (norfloxacin, ofloxacin, and ciprofloxacin), one sulfonamide (sulfamethoxazole… 
Highly Cited
2006
Highly Cited
2006
Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters.
Review
2003
Review
2003
Trimethoprim-sulfamethoxazole revisited.
During the past 3 decades, the combination of trimethoprim and sulfamethoxazole has occupied a central role in the treatment of… 
Highly Cited
2000
Highly Cited
2000
Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin.
The effects of mecillinam, trimethoprim and ciprofloxacin, antibiotics used in the treatment of urinary tract infections, on the… 
Highly Cited
1968
Highly Cited
1968
Trimethoprim, a sulphonamide potentiator.
The sulphonamides maintain a considerable place, relatively constant in scope, in the armamentarium of agents useful in bacterial… 
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