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Trimethoprim
Known as:
Trimetoprima
, 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
, Trimethoprimum
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A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial…
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National Institutes of Health
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Related topics
Related topics
44 relations
Anemia, Megaloblastic
Bacterial Infections
Bronchitis
Escherichia coli Infections
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Broader (3)
Anti-Bacterial Agents
Antimalarials
diaminopyrimidine
Narrower (17)
Bactrim
Polymyxin B / Trimethoprim
Polytrim
Polytrim eyedrops
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.
R. Loos
,
R. Carvalho
,
+15 authors
B. Gawlik
Water Research
2013
Corpus ID: 23163505
Highly Cited
2007
Highly Cited
2007
Removal of antibiotics in conventional and advanced wastewater treatment: implications for environmental discharge and wastewater recycling.
A. Watkinson
,
E. Murby
,
S. Costanzo
Water Research
2007
Corpus ID: 36353246
Review
2006
Review
2006
The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment.
P. H. Roberts
,
K. Thomas
Science of the Total Environment
2006
Corpus ID: 20625909
Highly Cited
2005
Highly Cited
2005
Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment.
Anke Göbel
,
A. Thomsen
,
Christa S. McArdell
,
A. Joss
,
W. Giger
Environmental Science and Technology
2005
Corpus ID: 20487141
The occurrence of sulfonamide and macrolide antimicrobials, as well as trimethoprim, was investigated in conventional activated…
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Review
2001
Review
2001
Resistance to trimethoprim-sulfamethoxazole.
G. Eliopoulos
,
P. Huovinen
Clinical Infectious Diseases
2001
Corpus ID: 6502551
Sulfonamides have a glorious history. In 1935, they were the first class of true antimicrobial agents with life-saving potency…
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Review
2001
Review
2001
Resistance to trimethoprim and sulfonamides.
O. Sköld
Veterinary Research
2001
Corpus ID: 1791859
Sulfonamides and trimethoprim have been used for many decades as efficient and inexpensive antibacterial agents for animals and…
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Highly Cited
1997
Highly Cited
1997
The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials.
H. Bucher
,
G. Guyatt
,
L. Griffith
,
S. Walter
Journal of Clinical Epidemiology
1997
Corpus ID: 8263044
Highly Cited
1996
Highly Cited
1996
Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis
C. Stegeman
,
J. Tervaert
,
D. Jong
,
C. Kallenberg
1996
Corpus ID: 78526852
Background Respiratory tract infections may trigger relapses in patients with Wegener's granu-lomatosis in remission…
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Review
1995
Review
1995
Trimethoprim and sulfonamide resistance
P. Huovinen
,
L. Sundström
,
G. Swedberg
,
O. Sköld
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 28489848
Trimethoprim (TMP) and sulfonamides (SULs) are synthetic antibacterial agents. The first SUL compounds were used in 1932, whereas…
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Highly Cited
1988
Highly Cited
1988
Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system
P. Dauber-Osguthorpe
,
V. Roberts
,
D. Osguthorpe
,
Jon Wolff
,
Moniqe Genest
,
A. Hagler
Proteins: Structure, Function, and Bioinformatics
1988
Corpus ID: 2845395
A study of the binding of the antibacterial agent trimethoprim to Escherichia coli dihydrofolate reductase was carried out using…
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