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Trimethoprim

Known as: Trimetoprima, 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine, Trimethoprimum 
A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
The spatiotemporal resolution of subdiffraction fluorescence imaging has been limited by the difficulty of labeling proteins in… Expand
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Highly Cited
2007
Highly Cited
2007
The elimination of sulfonamides, macrolides and trimethoprim from raw wastewater was investigated in several municipal wastewater… Expand
Highly Cited
2005
Highly Cited
2005
The occurrence of sulfonamide and macrolide antimicrobials, as well as trimethoprim, was investigated in conventional activated… Expand
Highly Cited
2002
Highly Cited
2002
A fast and cost effective method was developed to extract and quantify residues of veterinary antimicrobial agents (antibiotics… Expand
Review
2001
Review
2001
  • P. Huovinen
  • Clinical infectious diseases : an official…
  • 2001
  • Corpus ID: 6502551
Sulfonamides have a glorious history. In 1935, they were the first class of true antimicrobial agents with life-saving potency… Expand
  • table 1
Review
2001
Review
2001
  • O. Sköld
  • Veterinary research
  • 2001
  • Corpus ID: 1791859
Sulfonamides and trimethoprim have been used for many decades as efficient and inexpensive antibacterial agents for animals and… Expand
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Highly Cited
1996
Highly Cited
1996
Background Respiratory tract infections may trigger relapses in patients with Wegener's granu-lomatosis in remission… Expand
Review
1995
Review
1995
Trimethoprim (TMP) and sulfonamides (SULs) are synthetic antibacterial agents. The first SUL compounds were used in 1932, whereas… Expand
Highly Cited
1990
Highly Cited
1990
however, it is best that the concentrated necrotising venom is allowed to diffuse freely away from the region. Deaths due to the… Expand
Highly Cited
1988
Highly Cited
1988
  • Pnina Dauber‐Osguthorpe, Victoria A. Roberts, David J. Osguthorpe, Jon Wolff, Moniqe Genest, Arnold T. Hagler
  • Proteins
  • 1988
  • Corpus ID: 2845395
A study of the binding of the antibacterial agent trimethoprim to Escherichia coli dihydrofolate reductase was carried out using… Expand