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Trimethoprim

Known as: Trimetoprima, 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine, Trimethoprimum 
A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The occurrence of sulfonamide and macrolide antimicrobials, as well as trimethoprim, was investigated in conventional activated… 
Review
2001
Review
2001
  • P. Huovinen
  • Clinical infectious diseases : an official…
  • 2001
  • Corpus ID: 6502551
Sulfonamides have a glorious history. In 1935, they were the first class of true antimicrobial agents with life-saving potency… 
Highly Cited
1996
Highly Cited
1996
Background Respiratory tract infections may trigger relapses in patients with Wegener's granu-lomatosis in remission… 
Review
1995
Review
1995
Trimethoprim (TMP) and sulfonamides (SULs) are synthetic antibacterial agents. The first SUL compounds were used in 1932, whereas… 
Highly Cited
1988
Highly Cited
1988
A study of the binding of the antibacterial agent trimethoprim to Escherichia coli dihydrofolate reductase was carried out using… 
Highly Cited
1968
Highly Cited
1968
The sulphonamides maintain a considerable place, relatively constant in scope, in the armamentarium of agents useful in bacterial…