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Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments.
RQ was applied as a novel approach to estimate the environmental risk of pharmaceuticals that are most frequently detected in wastewater effluents, surface waters and sediments and its continuous introduction in the environment may make them "pseudopersistents". Expand
Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.
The results obtained for the solid phase indicated that MBR wastewater treatment yielding higher biodegradation rate could reduce the load of pollutants in the sludge, and sorption to sludge could be a relevant removal pathway only for several compounds. Expand
Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and
The developed analytical method was successfully applied to the analysis of pharmaceutical residues in WWTP influents and effluents, as well as in river water, and justifying the selection of internal standard calibration as the most suitable approach for this study. Expand
Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment.
Most of the substances are incomplete and improvements of the wastewater treatment and subsequent treatments of the produced sludge are required to prevent the introduction of these micro-pollutants in the environment. Expand
Drugs of abuse and their metabolites in the Ebro River basin: occurrence in sewage and surface water, sewage treatment plants removal efficiency, and collective drug usage estimation.
Overall, total levels of the studied illicit drugs and metabolites observed in surface water were one and two orders of magnitude lower than those determined in effluent and influent sewage water (microg/L range), respectively. Expand
Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid
The present work describes the development of an analytical method, based on automated off-line solid phase extraction (SPE) followed by ultra-high-performance liquid chromatography coupled toExpand
Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters.
A multi-residue analytical method has been developed and validated for determining a selection of 16 pharmaceuticals: the anti-epileptic carbamazepine, seven analgesic/anti-inflammatory drugs, the analgesic opiate codeine, two antidepressants, beta-blockers, and antibiotic in hospital effluent wastewater samples. Expand
Hospital effluent: investigation of the concentrations and distribution of pharmaceuticals and environmental risk assessment.
An environmental risk assessment revealed a high risk for 9 pharmaceuticals in hospital effluent and for 4 of the 9 substances in the treatment plant influent and effluent, with antibiotics being the most critical compounds in terms of contribution and potential environmental risk for the hospital. Expand
Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor
Drugs were, in general, removed to a greater extent by the MBR integrated system than during the CAS process, and the antiepileptic drug carbamazepine was the most persistent pharmaceutical. Expand
Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: identification of ecologically relevant pharmaceuticals.
Analysis of individual contributions of each therapeutic group showed that NSAIDs, analgesics and antibiotics are among the groups with the highest inputs, showing that pharmaceuticals are widespread pollutants in both hospital and urban wastewaters. Expand