diaminopyrimidine

Known as: DAP 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
05101519522016

Papers overview

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2011
2011
BACKGROUND AND PURPOSE P2X3 and P2X2/3 receptors are highly localized on the peripheral and central pathways of nociceptive… (More)
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2009
2009
It is important to understand the regulation of stem cell division because defects in this process can cause altered tissue… (More)
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2009
2009
The purinoceptor subtypes P2X(3) and P2X(2/3) have been shown to play a pivotal role in models of various pain conditions… (More)
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2008
2008
Arpida Ltd, under license from Roche AG, is developing the diaminopyrimidine dihydrofolate reductase inhibitor iclaprim for the… (More)
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2007
2007
Renin is an aspartyl protease involved in the production of angiotensin II, a potent vasoconstrictor. Renin inhibitors can… (More)
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Highly Cited
2004
Highly Cited
2004
A phenotypic cell-based screen of a large combinatorial chemical library led to the identification of a class of… (More)
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2003
2003
Iclaprim, a new selective dihydrofolate inhibitor was synthesized based on rational drug design. Iclaprim's interaction with a… (More)
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1996
1996
The reaction of guanidine hydrochloride with cyanoacetaldehyde gives high yields (40–85%) of 2,4-diaminopyrimidine under the… (More)
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1994
1994
This paper is devoted to chemotherapy in the sense that Paul Ehrlich (Nobel Prize winner in 1908) coined the word: to describe… (More)
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1977
1977
On the basis of activity against experimental tumors and potency as inhibitors of human dihydrofolate reductase, two compounds… (More)
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