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Trichlormethiazide

Known as: 3-Dichloromethylhydrochlorothiazide, Trichloromethiazide, Triclordiuride 
A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
National Institutes of Health

Related topics

Related topics

24 relations

Broader (2)

Antihypertensive AgentsDiuretics
AnuriaCongestive heart failureDecreased Blood Pressure [PE]Drug Allergy
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Narrower (5)

DiureseEsmaloridNaquaTriazide
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Papers overview

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2009
2009
Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the…
Thiazide and high ceiling diuretics were recently shown to inhibit all mammalian isoforms of carbonic anhydrase (CA, EC 4.2.1.1… Expand
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2006
2006
High-speed gas chromatography in doping control: fast-GC and fast-GC/MS determination of beta-adrenoceptor ligands and diuretics.
In official doping controls, about 300 drugs and metabolites have to be screened for each sample. Moreover, the number of… Expand
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Highly Cited
2006
Highly Cited
2006
Angiotensin II Type 1 Receptor Blockers Reduce Urinary Oxidative Stress Markers in Hypertensive Diabetic Nephropathy
We tested the hypothesis that blockade of angiotensin II type 1 receptors reduces oxidative stress markers in parallel with… Expand
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2004
2004
Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography.
A comparative study on the performance of two RPLC modes on the separation of 18 diuretics with diverse acid-base behaviour… Expand
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Highly Cited
2004
Highly Cited
2004
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide
AbstractResults: Incubation in vitro of human recombinant and erythrocyte (RBC) thiopurine methyl transferase (TPMT) with… Expand
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Highly Cited
2004
Highly Cited
2004
Interactions of Human Organic Anion Transporters with Diuretics
The tubular secretion of diuretics in the proximal tubule has been shown to be critical for the action of drugs. To elucidate the… Expand
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Highly Cited
1991
Highly Cited
1991
Antihypertensive effects of cicletanine and renal protection in Dahl salt-sensitive rats.
We designed experiments to reveal the antihypertensive properties of cicletanine, a novel antihypertensive drug, in Dahl salt… Expand
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Highly Cited
1988
Highly Cited
1988
Effects of first‐line antihypertensive agents on sexual function and sex hormones
We studied sexual dysfunction induced by antihypertensive agents in 156 male hypertensive patients. The antihypertensive agents… Expand
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Highly Cited
1988
Highly Cited
1988
Site and mechanism of action of trichlormethiazide in rabbit distal nephron segments perfused in vitro.
To determine the exact site and mechanism of action of thiazide diuretics, effects of 10(-4) M trichlormethiazide (TCM) on NaCl… Expand
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Highly Cited
1983
Highly Cited
1983
Importance of increased urinary calcium excretion in the development of secondary hyperparathyroidism of patients under glucocorticoid therapy.
Parathyroid function and calcium metabolism were studied in 44 patients under glucocorticoid therapy (steroid group) and in 25… Expand
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