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The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014)
Kazuaki SHIMAMOTO, Katsuyuki ANDO, Toshiro FUJITA, Naoyuki HASEBE, Jitsuo HIGAKI, Masatsugu HORIUCHI, Yutaka IMAI, Tsutomu IMAIZUMI, Toshihiko ISHIMITSU, Masaaki ITO, Sadayoshi ITO, Hiroshi ITOH,Expand
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The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Satoshi Umemura ● Hisatomi Arima ● Shuji Arima ● Kei Asayama ● Yasuaki Dohi ● Yoshitaka Hirooka ● Takeshi Horio ● Satoshi Hoshide ● Shunya Ikeda ● Toshihiko Ishimitsu ● Masaaki Ito ● Sadayoshi Ito ●Expand
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Efficacy and Safety of a Novel ĸ-Agonist for Managing Intractable Pruritus in Dialysis Patients
Background: Our previous placebo-controlled, prospective, double-blind study demonstrated that a new opioid ĸ-receptor agonist, nalfurafine hydrochloride, effectively reduced treatment-resistantExpand
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Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure
Accentuated sympathetic nerve activity (SNA) is a risk factor for cardiovascular events. In this review, we investigate our working hypothesis that potentiated activity of neurons in the rostralExpand
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Three types of putative presympathetic neurons in the rostral ventrolateral medulla studied with rat brainstem–spinal cord preparation
To study the electrophysiological properties of presympathetic neurons in the rostral ventrolateral medulla (RVLM), intracellular recordings were performed by the whole-cell patch-clamp technique. WeExpand
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Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study.
BACKGROUND Pruritus in haemodialysis patients is an intractable disease and substantially impairs their quality of life. Based on the results of our earlier clinical study, we hypothesized that theExpand
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Altered renal microvascular response in Zucker obese rats.
Although available evidence demonstrates that obesity manifests insulin resistance and causes glomerular sclerosis, it has not been determined whether insulin resistance alters the renalExpand
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Impaired nitric oxide‐ and endothelium‐derived hyperpolarizing factor‐dependent dilation of renal afferent arteriole in Dahl salt‐sensitive rats
Background and Aims:  We previously demonstrated that acetylcholine elicited nitric oxide‐dependent sustained and endothelium‐derived hyperpolarizing factor (EDHF)‐dependent transient dilation ofExpand
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Serial Manifestation of Acute Kidney Injury and Nephrotic Syndrome in a Patient with TAFRO Syndrome
A 76-year-old woman suddenly developed anasarca and a fever, and an examination revealed thrombocytopenia, reticulin fibrosis, and acute kidney injury, yielding the diagnosis of thrombocytopenia,Expand
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The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension
Toshio OGIHARA, Kenjiro KIKUCHI, Hiroaki MATSUOKA, Toshiro FUJITA, Jitsuo HIGAKI, Masatsugu HORIUCHI, Yutaka IMAI, Tsutomu IMAIZUMI, Sadayoshi ITO, Hiroshi IWAO, Kazuomi KARIO, Yuhei KAWANO, ShokeiExpand
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