Tranylcypromine

Known as: trans 2 Phenylcyclopropylamine, Tranilcipromina, Tranylcypromine [Chemical/Ingredient] 
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential… (More)
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Highly Cited
2010
Highly Cited
2010
LSD1 and LSD2 histone demethylases are implicated in a number of physiological and pathological processes, ranging from… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE The purpose of this study was to compare the effectiveness and tolerability of tranylcypromine and combination… (More)
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Highly Cited
2006
Highly Cited
2006
Demethylation of histone H3 lysine 4 is carried out by BHC110/LSD1, an enzyme with close homology to monoamine oxidases (MAO… (More)
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Highly Cited
2004
Highly Cited
2004
STAR*D is a multisite, prospective, randomized, multistep clinical trial of outpatients with nonpsychotic major depressive… (More)
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Review
2004
Review
2004
Monoamine oxidases A and B (MAO A and MAO B) are mitochondrial outer membrane-bound flavoproteins that catalyze the oxidative… (More)
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Highly Cited
2000
Highly Cited
2000
Regulation of gene transcription via the cAMP-mediated second messenger pathway has been implicated in the actions of… (More)
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Highly Cited
1995
Highly Cited
1995
The influence of chronic electroconvulsive seizure (ECS) or antidepressant drug treatments on expression of brain-derived… (More)
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Highly Cited
1991
Highly Cited
1991
OBJECTIVE This investigation compared the efficacy of the monoamine oxidase inhibitor (MAOI) tranylcypromine with that of the… (More)
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1988
1988
Thirty-two patients meeting DSM-III criteria for social phobia entered a 1-year drug treatment with tranylcypromine in dosages… (More)
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