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Tranylcypromine

Known as: trans 2 Phenylcyclopropylamine, Tranilcipromina, Tranylcypromine [Chemical/Ingredient] 
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
LSD1 and LSD2 histone demethylases are implicated in a number of physiological and pathological processes, ranging from… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE The purpose of this study was to compare the effectiveness and tolerability of tranylcypromine and combination… Expand
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Highly Cited
2004
Highly Cited
2004
STAR*D is a multisite, prospective, randomized, multistep clinical trial of outpatients with nonpsychotic major depressive… Expand
Highly Cited
2003
Highly Cited
2003
Monoamine oxidase B (MAO-B) is an outer mitochondrial membrane-bound enzyme that catalyzes the oxidative deamination of… Expand
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Highly Cited
1998
Highly Cited
1998
Mean effect sizes for changes in depression were calculated for 2,318 patients who had been randomly assigned to either… Expand
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Highly Cited
1995
Highly Cited
1995
The influence of chronic electroconvulsive seizure (ECS) or antidepressant drug treatments on expression of brain-derived… Expand
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Highly Cited
1991
Highly Cited
1991
OBJECTIVE This investigation compared the efficacy of the monoamine oxidase inhibitor (MAOI) tranylcypromine with that of the… Expand
Highly Cited
1984
Highly Cited
1984
1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) causes degeneration of the dopaminergic nigrostriatal pathway in several… Expand
Highly Cited
1976
Highly Cited
1976
Prostaglandin (PG) endoperoxides (PGG2 and PGH2) contract arterial smooth muscle and cause platelet aggregation. Microsomes from… Expand
Highly Cited
1970
Highly Cited
1970
1. In mucosa‐free preparations of the detrusor muscle electrical stimulation with 0·1 msec pulses has been utilized to reveal the… Expand