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Trans-Activators

Known as: Transactivators, Trans Acting Factor, Trans Acting Factors 
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
National Institutes of Health

Related topics

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Narrower (46)

ATXA protein, Bacillus anthracisAc-IE-2 protein, Autographa californica nucleopolyhedrovirusAgpT protein, Sinorhizobium melilotiAsnC protein, E coli
Process of secretionagonistsantagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
2001
Highly Cited
2001
Chemical-regulated, site-specific DNA excision in transgenic plants
We have developed a chemical-inducible, site-specific DNA excision system in transgenic Arabidopsis plants mediated by the Cre… 
Review
1996
Review
1996
Regulation of gene expression by insulin.
While insulin has long been known to modulate intracellular metabolism by altering the activity or intracellular location of… 
Highly Cited
1993
Highly Cited
1993
The role of exon sequences in splice site selection.
Using mouse immunoglobulin mu (IgM) pre-mRNA as the model substrate for in vitro splicing, we have explored the role of exon… 
Highly Cited
1991
Highly Cited
1991
Activation of BPV-1 replication in vitro by the transcription factor E2
Soluble extracts from uninfected murine cells supplemented with purified viral E1 and E2 proteins support the replication of… 
Highly Cited
1989
Highly Cited
1989
The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16
The herpes simplex virus transactivator VP16 par-ticipates in the formation of a multiprotein-DNA complex with the ubiquitous… 
Highly Cited
1988
Highly Cited
1988
A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen
Several Epstein-Barr virus (EBV) early promoters respond to a new EBV transactivator encoded by BRLF1, designated R… 
Highly Cited
1987
Highly Cited
1987
Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos
Highly Cited
1987
Highly Cited
1987
Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements
We identified and characterized elements which confer tissue specificity and cyclic AMP (cAMP) responsiveness to the human… 
Highly Cited
1987
Highly Cited
1987
A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator
Highly Cited
1985
Highly Cited
1985
Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene.
A HeLa cell transient-expression assay system was used to determine if isolated immediate early (alpha) genes from herpes simplex… 
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