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Trans-Activators

Known as: Transactivators, Trans Acting Factor, Trans Acting Factors 
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
National Institutes of Health

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Narrower (46)

ATXA protein, Bacillus anthracisAc-IE-2 protein, Autographa californica nucleopolyhedrovirusAgpT protein, Sinorhizobium melilotiAsnC protein, E coli
Process of secretionagonistsantagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
1998
Highly Cited
1998
Perinuclear localization of chromatin facilitates transcriptional silencing
Transcriptional silencing in Saccharomyces cerevisiae at the HM mating-type loci and telomeres occurs through the formation of a… 
Highly Cited
1996
Highly Cited
1996
Genetic determinants of p53-induced apoptosis and growth arrest.
Previous studies have suggested that expression of p53 in cancer cells can result in either growth arrest or apoptosis… 
Highly Cited
1992
Highly Cited
1992
A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s.
Highly Cited
1991
Highly Cited
1991
The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon.
mRNA decay rates often increase when translation is terminated prematurely due to a frameshift or nonsense mutation. We have… 
Highly Cited
1989
Highly Cited
1989
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
More than 20 different cDNA clones encoding DNA-damage-inducible transcripts in rodent cells have recently been isolated by… 
Highly Cited
1988
Highly Cited
1988
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.
Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally… 
Highly Cited
1987
Highly Cited
1987
12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region
Genomic clones coding for human fibroblast collagenase were isolated. By constructing and transfecting mutants with 5' and 3… 
Highly Cited
1986
Highly Cited
1986
The trans-activator gene of HTLV-III is essential for virus replication
Studies of the genomic structure of human T-lymphotropic virus type III (HTLV-III) and related viruses, implicated as the causal… 
Highly Cited
1985
Highly Cited
1985
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).
Human T-lymphotropic virus type III (HTLV-III) encodes a trans-acting factor that activates the expression of genes linked to the… 
Highly Cited
1983
Highly Cited
1983
Vectors for P element-mediated gene transfer in Drosophila.
We have constructed and tested several new vectors for P element-mediated gene transfer. These vectors contain restriction sites… 
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