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Trans-Activators
Known as:
Transactivators
, Trans Acting Factor
, Trans Acting Factors
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Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (46)
ATXA protein, Bacillus anthracis
Ac-IE-2 protein, Autographa californica nucleopolyhedrovirus
AgpT protein, Sinorhizobium meliloti
AsnC protein, E coli
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Process of secretion
agonists
antagonists & inhibitors
chemical synthesis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The biogenesis, biology and characterization of circular RNAs
L. Kristensen
,
M. S. Andersen
,
L. V. W. Stagsted
,
K. K. Ebbesen
,
T. B. Hansen
,
J. Kjems
Nature reviews genetics
2019
Corpus ID: 199491832
Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes with tissue-specific and cell-specific…
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Highly Cited
2007
Highly Cited
2007
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Junying Yu
,
M. Vodyanik
,
+9 authors
J. Thomson
Science
2007
Corpus ID: 15939215
Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an…
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Highly Cited
2005
Highly Cited
2005
microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
E. Allen
,
Zhixin Xie
,
Adam M. Gustafson
,
J. Carrington
Cell
2005
Corpus ID: 18056486
Review
2000
Review
2000
CBP/p300 in cell growth, transformation, and development.
R. Goodman
,
S. Smolik
Genes & Development
2000
Corpus ID: 28477108
CREB binding protein (CBP) and p300 were both identified initially in protein interaction assays–the former through its…
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Highly Cited
1997
Highly Cited
1997
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
M. Hendzel
,
Yi Wei
,
+5 authors
C. Allis
Chromosoma
1997
Corpus ID: 29723188
Abstract. We have generated and characterized a novel site-specific antibody highly specific for the phosphorylated form of the…
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Highly Cited
1995
Highly Cited
1995
Transcriptional activation by tetracyclines in mammalian cells.
M. Gossen
,
S. Freundlieb
,
G. Bender
,
G. Müller
,
W. Hillen
,
H. Bujard
Science
1995
Corpus ID: 24871484
A transcriptional transactivator was developed that fuses the VP16 activation domain with a mutant Tet repressor from Escherichia…
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Highly Cited
1992
Highly Cited
1992
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
M. Gossen
,
H. Bujard
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 37196165
Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a…
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Highly Cited
1989
Highly Cited
1989
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
M. Malim
,
J. Hauber
,
S. Le
,
J. Maizel
,
B. Cullen
Nature
1989
Corpus ID: 4367958
HUMAN immunodeficiency virus type 1 (HIV-1) replication requires the expression of two classes of viral mRNA. The early class of…
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Highly Cited
1988
Highly Cited
1988
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.
S. Triezenberg
,
R. Kingsbury
,
S. McKnight
Genes & Development
1988
Corpus ID: 35417339
Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally…
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Highly Cited
1987
Highly Cited
1987
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
P. Angel
,
M. Imagawa
,
+6 authors
M. Karin
Cell
1987
Corpus ID: 23154076
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