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Trans-Activators

Known as: Transactivators, Trans Acting Factor, Trans Acting Factors 
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
National Institutes of Health

Related topics

Related topics

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Narrower (46)

ATXA protein, Bacillus anthracisAc-IE-2 protein, Autographa californica nucleopolyhedrovirusAgpT protein, Sinorhizobium melilotiAsnC protein, E coli
Process of secretionagonistsantagonists & inhibitorschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The biogenesis, biology and characterization of circular RNAs
Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes with tissue-specific and cell-specific… 
Highly Cited
2007
Highly Cited
2007
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an… 
Highly Cited
2005
Highly Cited
2005
microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
Review
2000
Review
2000
CBP/p300 in cell growth, transformation, and development.
CREB binding protein (CBP) and p300 were both identified initially in protein interaction assays–the former through its… 
Highly Cited
1997
Highly Cited
1997
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
Abstract. We have generated and characterized a novel site-specific antibody highly specific for the phosphorylated form of the… 
Highly Cited
1995
Highly Cited
1995
Transcriptional activation by tetracyclines in mammalian cells.
A transcriptional transactivator was developed that fuses the VP16 activation domain with a mutant Tet repressor from Escherichia… 
Highly Cited
1992
Highly Cited
1992
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
  • M. GossenH. Bujard
  • Proceedings of the National Academy of Sciences…
  • 1992
  • Corpus ID: 37196165
Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a… 
Highly Cited
1989
Highly Cited
1989
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
HUMAN immunodeficiency virus type 1 (HIV-1) replication requires the expression of two classes of viral mRNA. The early class of… 
Highly Cited
1988
Highly Cited
1988
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.
Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally… 
Highly Cited
1987
Highly Cited
1987
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
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