Trans-Activators

Known as: Transactivators, Trans Acting Factor, Trans Acting Factors 
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an… (More)
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Highly Cited
2005
Highly Cited
2005
Plants and animals use small RNAs (microRNAs [miRNAs] and siRNAs) as guides for posttranscriptional and epigenetic regulation. In… (More)
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Highly Cited
2000
Highly Cited
2000
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, or statins, are effective lipid-lowering agents… (More)
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Highly Cited
1995
Highly Cited
1995
A transcriptional transactivator was developed that fuses the VP16 activation domain with a mutant Tet repressor from Escherichia… (More)
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Highly Cited
1992
Highly Cited
1992
Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a… (More)
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Highly Cited
1989
Highly Cited
1989
HUMAN immunodeficiency virus type 1 (HIV-1) replication requires the expression of two classes of viral mRNA. The early class of… (More)
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Highly Cited
1988
Highly Cited
1988
HIV-1 encodes a potent trans-activator protein, tat, which is essential for viral gene expression. To study tat domains that… (More)
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Highly Cited
1988
Highly Cited
1988
Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally… (More)
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Highly Cited
1987
Highly Cited
1987
The promoter regions of several phorbol diester-(TPA-) inducible genes (collagenase, stromelysin, hMT IIA, and SV40) share a… (More)
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Highly Cited
1987
Highly Cited
1987
Human immunodeficiency virus (HIV) production from latently infected T lymphocytes can be induced with compounds that activate… (More)
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