Tosylphenylalanyl Chloromethyl Ketone

Known as: Chlorophenyltosylamidobutanone, Chloromethyl Ketone, Tosylphenylalanyl, Chloromethane, Tosylphenylalanyl 
An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
010203019692018

Papers overview

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Highly Cited
2006
Highly Cited
2006
Research in the area of educational technology has often been critiqued for a lack of theoretical grounding. In this article we… (More)
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Highly Cited
2005
Highly Cited
2005
Preservice teachers’ pedagogical content knowledge (PCK) development was investigated with respect to integrating technology… (More)
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Highly Cited
2002
Highly Cited
2002
The ubiquitously expressed transcription factor NF-kappa B and the serine-threonine kinase Akt both are involved in the promotion… (More)
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Highly Cited
2000
Highly Cited
2000
Apaf-1, by binding to and activating caspase-9, plays a critical role in apoptosis. Oligomerization of Apaf-1, in the presence of… (More)
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Highly Cited
1999
Highly Cited
1999
Interleukin-6 (IL-6) is a multifunctional cytokine expressed by angiotensin II (Ang II)-stimulated vascular smooth muscle cells… (More)
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Highly Cited
1999
Highly Cited
1999
The Rel/NF-κB transcription factors regulate the expression of many genes. The activity of RelA, a member of the Rel/NF-κB… (More)
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Highly Cited
1997
Highly Cited
1997
Autolytic DNA breakdown, detected as smears in electrophoretic gels, is a late event in necrosis. On the other hand… (More)
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Highly Cited
1996
Highly Cited
1996
Apoptosis of the WEHI 231 immature B cell lymphoma line following membrane interaction with an antibody against the surface IgM… (More)
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Highly Cited
1995
Highly Cited
1995
Human leukemia U937 cells are induced to undergo apoptosis by several chemotherapeutic agents; however, the cellular components… (More)
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Highly Cited
1992
Highly Cited
1992
The appearance of DNA strand breaks during apoptosis was detected in individual cells, in relation to the cell cycle phase, by a… (More)
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