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Tissue Inhibitor of Metalloproteinase-3
Known as:
Metalloproteinase-3 Tissue Inhibitor
, Tissue Inhibitor of Metalloproteinase-3 [Chemical/Ingredient]
, Tissue Inhibitor of Metalloproteinase 3
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A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PROTEIN causes Sorsby fundus dystrophy.
National Institutes of Health
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Related topics
Related topics
12 relations
In Blood
Process of secretion
TIMP3 gene
agonists
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Broader (2)
Matrix Metalloproteinase Inhibitors
Proteins
Narrower (1)
TIMP3 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The imbalance between TIMP3 and matrix-degrading enzymes plays an important role in intervertebral disc degeneration.
Y. Li
,
Kang-Ming Li
,
+4 authors
Jie Zhao
Biochemical and Biophysical Research…
2016
Corpus ID: 21856506
Highly Cited
2013
Highly Cited
2013
SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
H. Yao
,
Jae-woong Hwang
,
+6 authors
I. Rahman
American Journal of Physiology - Lung cellular…
2013
Corpus ID: 403384
Sirtuin1 (SIRT1), a protein/histone deacetylase, protects against the development of pulmonary emphysema. However, the molecular…
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2011
2011
The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis.
K. Andersen
,
H. Mori
,
+4 authors
M. Bissell
Developmental Biology
2011
Corpus ID: 205739602
Highly Cited
2008
Highly Cited
2008
Tissue inhibitor of metalloproteinases-3 interacts with angiotensin II type 2 receptor and additively inhibits angiogenesis.
K. Kang
,
Sang-Yoon Park
,
S. Rho
,
Je‐ho Lee
Cardiovascular Research
2008
Corpus ID: 24989309
AIM The tissue inhibitors of metalloproteinases (TIMPs) are complex molecules with both pro- and anti-tumour effects. Thus, their…
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Highly Cited
2005
Highly Cited
2005
Total Conversion of Tissue Inhibitor of Metalloproteinase (TIMP) for Specific Metalloproteinase Targeting
Meng H Lee
,
M. Rapti
,
G. Murphy
Journal of Biological Chemistry
2005
Corpus ID: 6961865
Tissue inhibitors of metalloproteinases (TIMPs) are the endogenous inhibitors of the matrix metalloproteinases, the ADAMs…
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Highly Cited
2004
Highly Cited
2004
DNA methylation of multiple promoter-associated CpG islands in meningiomas: relationship with the allelic status at 1p and 22q
M. Bello
,
C. Amiñoso
,
+11 authors
Juan A. Rey
Acta Neuropathologica
2004
Corpus ID: 9064128
The purpose of this research was to examine the DNA methylation profile of meningiomas. Accordingly, we examined the DNA…
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Highly Cited
2003
Highly Cited
2003
TIMP‐3 inhibits aggrecanase‐mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors
C. Gendron
,
M. Kashiwagi
,
C. Hughes
,
B. Caterson
,
H. Nagase
FEBS Letters
2003
Corpus ID: 31803369
Highly Cited
2003
Highly Cited
2003
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
vander Laan
,
P. Quax
,
+9 authors
T. Pap
Gene Therapy
2003
Corpus ID: 36279821
Matrix metalloproteinases (MMPs) are believed to be pivotal enzymes in the invasion of articular cartilage by synovial tissue in…
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2002
2002
Adenovirus mediated gene delivery of tissue inhibitor of metalloproteinases-3 induces death in retinal pigment epithelial cells
M. Majid
,
V. Smith
,
D. Easty
,
A. Baker
,
A. Newby
British Journal of Ophthalmology
2002
Corpus ID: 17633193
Background: Sorsby's fundus dystrophy (SFD) and age related macular degeneration (ARMD) are retinal diseases associated with a…
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Highly Cited
1995
Highly Cited
1995
92‐kDa type IV collagenase and TIMP‐3, but not 72‐kDa type IV collagenase or TIMP‐1 or TIMP‐2, are highly expressed during mouse embryo implantation
P. Reponen
,
I. Leivo
,
+4 authors
K. Tryggvason
Developmental Dynamics
1995
Corpus ID: 25034415
Expression of 72 kDa and 92 kDa type IV collagenases and the metalloproteinase inhibitors TIMPs 1, 2, and 3 was studied by in…
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