Tissue Inhibitor of Metalloproteinase-3

Known as: Metalloproteinase-3 Tissue Inhibitor, Tissue Inhibitor of Metalloproteinase-3 [Chemical/Ingredient], Tissue Inhibitor of Metalloproteinase 3 
A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PROTEIN causes Sorsby fundus dystrophy.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
05101519922018

Papers overview

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2008
2008
Malignant solid tumors remain a significant clinical challenge, necessitating innovative therapeutic approaches. Oncolytic viral… (More)
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2008
2008
Matrix metalloproteinase-2 (MMP-2) expression is often up-regulated in advanced cancers and known to play an important role in… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND OBJECTIVES Mesenchymal stem cells (MSC) are adult stem cells that can be expanded many fold in vitro and have the… (More)
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2003
2003
Pulmonary lymphangioleiomyomatosis (LAM) is characterized by abnormal smooth muscle-like cell proliferation leading to tissue… (More)
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Highly Cited
2001
Highly Cited
2001
Tissue inhibitors of metalloproteinases regulate ECM degradation by matrix metalloproteinases (MMPs). We have developed a mouse… (More)
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Highly Cited
2000
Highly Cited
2000
Of the four known tissue inhibitors of metalloproteinases (TIMPs), TIMP-3 is distinguished by its tighter binding to the… (More)
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Highly Cited
1999
Highly Cited
1999
Tissue inhibitor of metalloproteinase-3 (TIMP-3) antagonizes matrix metalloproteinase activity and can suppress tumor growth… (More)
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1998
1998
BACKGROUND/AIMS Tissue inhibitor of metalloproteinases-3 (TIMP-3) is normally synthesised by the retinal pigment epithelium (RPE… (More)
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Highly Cited
1996
Highly Cited
1996
The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M… (More)
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Highly Cited
1994
Highly Cited
1994
We have isolated cDNA clones corresponding to a novel mouse metalloproteinase inhibitor. Five overlapping cDNA clones contain… (More)
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