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Matrix Metalloproteinase Inhibitors

Known as: Metalloproteinase Inhibitors, Matrix, Inhibitors, MMP, Matrix Metalloproteinase Inhibitor 
Any substance that inhibits matrix metalloproteinase (MMP), an endopeptidase that degrades components of the extracellular matrix during tissue… 
National Institutes of Health

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Narrower (28)

3,4,5-trihydroxybenzaldehyde4-des-dimethylaminotetracyclineCGS 27023CH1766
Collagenase InhibitorIn Bloodaspects of radiation effectschemical synthesis

Papers overview

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Highly Cited
2007
Highly Cited
2007
A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo.
AIM The non-invasive measurement of activated matrix metalloproteinases (MMPs) in vivo, which are involved in many… 
Review
2006
Review
2006
Natural bio-drugs as matrix metalloproteinase inhibitors: new perspectives on the horizon?
The matrix metalloproteinases (MMPs), belonging to the family of proteolytic enzymes, are well-known for their ability to degrade… 
2004
2004
Inward Remodeling of the Rabbit Aorta Is Blocked by the Matrix Metalloproteinase Inhibitor Doxycycline
Constrictive arterial remodeling accounts for a significant proportion of lumen loss in atherosclerotic progression and… 
Review
2003
Review
2003
Angiogenesis inhibitors under study for the treatment of lung cancer.
2002
2002
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
Enhanced expression and activation of matrix metalloproteinase-2 (MMP-2) and MMP-9 have been associated with tumor progression… 
Highly Cited
2002
Highly Cited
2002
The matrix metalloproteinase inhibitor BB-94 improves the strength of intestinal anastomoses in the rat
HeadingAbstract Background and aims. The strength of intestinal anastomoses is relatively low in the first days after operation… 
Highly Cited
1999
Highly Cited
1999
Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors.
BACKGROUND Fas ligand (FasL) is a transmembrane protein that induces apoptosis (programmed cell death) in susceptible cells by… 
1999
1999
The matrix metalloproteinase inhibitor BB‐1101 prevents experimental autoimmune uveoretinitis (EAU)
EAU is characterized by breakdown of the blood–retinal barrier and extravasation of leucocytes into retinal tissue leading to… 
1997
1997
Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein.
Matrix metalloproteinase-1 (MMP-1) and tissue matrix metalloproteinase inhibitor 1 (TIMP-1) play an important role in remodeling… 
Review
1994
Review
1994
Clinical Trials of a Low Molecular Weight Matrix Metalloproteinase Inhibitor in Cancer
Matrix metalloproteinases (MMPs) first received broad recognition as the proteinases thought to be responsible for joint… 
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