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Matrix Metalloproteinase Inhibitors
Known as:
Metalloproteinase Inhibitors, Matrix
, Inhibitors, MMP
, Matrix Metalloproteinase Inhibitor
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Any substance that inhibits matrix metalloproteinase (MMP), an endopeptidase that degrades components of the extracellular matrix during tissue…
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National Institutes of Health
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Related topics
Related topics
33 relations
Narrower (28)
3,4,5-trihydroxybenzaldehyde
4-des-dimethylaminotetracycline
CGS 27023
CH1766
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Collagenase Inhibitor
In Blood
aspects of radiation effects
chemical synthesis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo.
H. Breyholz
,
S. Wagner
,
B. Levkau
,
O. Schober
,
M. Schäfers
,
K. Kopka
The Quarterly Journal of Nuclear Medicine and…
2007
Corpus ID: 25055803
AIM The non-invasive measurement of activated matrix metalloproteinases (MMPs) in vivo, which are involved in many…
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Review
2006
Review
2006
Natural bio-drugs as matrix metalloproteinase inhibitors: new perspectives on the horizon?
F. Mannello
Recent Patents on Anti-Cancer Drug Discovery
2006
Corpus ID: 7385944
The matrix metalloproteinases (MMPs), belonging to the family of proteolytic enzymes, are well-known for their ability to degrade…
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2004
2004
Inward Remodeling of the Rabbit Aorta Is Blocked by the Matrix Metalloproteinase Inhibitor Doxycycline
D. Courtman
,
C. Franco
,
Q. Meng
,
M. Bendeck
Journal of Vascular Research
2004
Corpus ID: 39041153
Constrictive arterial remodeling accounts for a significant proportion of lumen loss in atherosclerotic progression and…
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Review
2003
Review
2003
Angiogenesis inhibitors under study for the treatment of lung cancer.
F. Shepherd
,
S. Sridhar
Lung Cancer
2003
Corpus ID: 36504815
2002
2002
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
E. Maquoi
,
C. Munaut
,
+6 authors
J. Foidart
Experimental Cell Research
2002
Corpus ID: 2241215
Enhanced expression and activation of matrix metalloproteinase-2 (MMP-2) and MMP-9 have been associated with tumor progression…
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Highly Cited
2002
Highly Cited
2002
The matrix metalloproteinase inhibitor BB-94 improves the strength of intestinal anastomoses in the rat
I. de Hingh
,
M. Siemonsma
,
B. D. de Man
,
R. Lomme
,
T. Hendriks
International Journal of Colorectal Disease
2002
Corpus ID: 21096606
HeadingAbstract Background and aims. The strength of intestinal anastomoses is relatively low in the first days after operation…
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Highly Cited
1999
Highly Cited
1999
Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors.
N. Mitsiades
,
V. Poulaki
,
A. Leone
,
M. Tsokos
Journal of the National Cancer Institute
1999
Corpus ID: 15303868
BACKGROUND Fas ligand (FasL) is a transmembrane protein that induces apoptosis (programmed cell death) in susceptible cells by…
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1999
1999
The matrix metalloproteinase inhibitor BB‐1101 prevents experimental autoimmune uveoretinitis (EAU)
G. Wallace
,
R. Whiston
,
M. Stanford
,
G. Wells
,
A. Gearing
,
J. Clements
Clinical and Experimental Immunology
1999
Corpus ID: 29241329
EAU is characterized by breakdown of the blood–retinal barrier and extravasation of leucocytes into retinal tissue leading to…
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1997
1997
Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein.
Gabriela Aust
,
A. Hofmann
,
S. Laue
,
A.-K. Rost
,
T. Köhler
,
W. A. Scherbaum
Thyroid
1997
Corpus ID: 25550167
Matrix metalloproteinase-1 (MMP-1) and tissue matrix metalloproteinase inhibitor 1 (TIMP-1) play an important role in remodeling…
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Review
1994
Review
1994
Clinical Trials of a Low Molecular Weight Matrix Metalloproteinase Inhibitor in Cancer
P. Brown
Annals of the New York Academy of Sciences
1994
Corpus ID: 36362650
Matrix metalloproteinases (MMPs) first received broad recognition as the proteinases thought to be responsible for joint…
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