Matrix Metalloproteinase Inhibitors

Known as: Metalloproteinase Inhibitors, Matrix, Inhibitors, MMP, Matrix Metalloproteinase Inhibitor 
Any substance that inhibits matrix metalloproteinase (MMP), an endopeptidase that degrades components of the extracellular matrix during tissue… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Matrix metalloproteinases (MMPs) disrupt the blood-brain barrier (BBB) during reperfusion. Occludin and claudins are recently… (More)
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Review
2006
Review
2006
The failure of matrix metalloproteinase (MMP) inhibitor drug clinical trials in cancer was partly due to the inadvertent… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Angiotensin II (AngII) infusion into hyperlipidemic mice leads to the rapid formation of atherosclerotic lesions and… (More)
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Review
2002
Review
2002
The matrix metalloproteinases represent an attractive target for cancer treatment, and a number of matrix metalloproteinase… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Novel therapies are needed for patients with recurrent glioblastoma multiforme (GBM). Because there is evidence that… (More)
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Highly Cited
2001
Highly Cited
2001
Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling. We previously found that a membrane… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To determine the effect of matrix metalloproteinase (MMP) inhibitors in mono-iodoacetate-induced arthritis in rats… (More)
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Highly Cited
2001
Highly Cited
2001
Overexpression of matrix metalloproteinases (MMPs) facilitates tumor cell invasion. Synthetic MMP inhibitors such as batimastat… (More)
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Review
1999
Review
1999
  • P D Brown
  • APMIS : acta pathologica, microbiologica, et…
  • 1999
Matrix metalloproteinases (MMPs) have been implicated in the invasive growth and spread of tumours. Potent and selective… (More)
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Review
1997
Review
1997
The matrix metalloproteinases (MMPs) are a family of at least fifteen secreted and membrane-bound zinc-endopeptidases… (More)
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