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TIMP3 gene

Known as: TISSUE INHIBITOR OF METALLOPROTEINASE 3, TIMP metallopeptidase inhibitor 3, TIMP3 
This gene plays a role in the degradation of the extracellular matrix. It is also involved in the induction of apoptosis and inhibition of… 
National Institutes of Health

Related topics

Related topics

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Angiogenic ProcessProtein Degradation InhibitionRegulation of ProteolysisTIMP3 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice
The current study presents an effective and selective multifunctional nanoparticle used to deliver antiatherogenic therapeutics… 
Highly Cited
2013
Highly Cited
2013
Promoter methylation and expression of TIMP3 gene in gastric cancer
BackgroundGastric carcinoma development is a multi-stage process that involves more than one gene. Aberrant changes in DNA… 
Highly Cited
2012
Highly Cited
2012
Overexpression of Tissue Inhibitor of Metalloproteinase 3 in Macrophages Reduces Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice
Objective— Tissue inhibitor of metalloproteinase 3 (TIMP3) is a stromal protein that inhibits the activity of proteases and… 
Highly Cited
2010
Highly Cited
2010
TIMP3: a physiological regulator of adult myogenesis
Myogenic differentiation in adult muscle is normally suppressed and can be activated by myogenic cues in a subset of activated… 
Highly Cited
2008
Highly Cited
2008
Multiple gene methylation of nonsmall cell lung cancers evaluated with 3‐dimensional microarray
Aberrant DNA methylation of the CpG islands for cancer‐related genes is among the earliest and most frequent alterations in… 
Highly Cited
2007
Highly Cited
2007
Expression profiles associated with aggressive behavior in Merkel cell carcinoma
Primary neuroendocrine carcinoma of the skin, or Merkel cell carcinoma, is the most aggressive cutaneous neoplasm. In spite of… 
Highly Cited
2006
Highly Cited
2006
Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology
Tissue inhibitors of matrix metalloproteinases (TIMPs) comprise a family of four members, of which TIMP4 is characterized by… 
Highly Cited
2006
Highly Cited
2006
Fetal Membranes From Term VAginal Deliveries Have a Zone of Weakness Exhibiting Characteristics of Apoptosis and Remodeling
Highly Cited
2004
Highly Cited
2004
Gene expression patterns associated with infertility in humans and rodent models.
Highly Cited
2001
Highly Cited
2001
CpG island methylation in premalignant stages of gastric carcinoma.
There are limited reports on methylation analysis of the premalignant lesions of gastric carcinoma thus far. This is despite the… 
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