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TIMP3 gene

Known as: TISSUE INHIBITOR OF METALLOPROTEINASE 3, TIMP metallopeptidase inhibitor 3, TIMP3 
This gene plays a role in the degradation of the extracellular matrix. It is also involved in the induction of apoptosis and inhibition of… 
National Institutes of Health

Related topics

Related topics

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Angiogenic ProcessProtein Degradation InhibitionRegulation of ProteolysisTIMP3 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Exosomes from microRNA-199-3p-modified adipose-derived stem cells promote proliferation and migration of endothelial tip cells by downregulation of semaphorin 3A.
Exosomes secreted by adipose-derived stem cells (ADSCs) have been shown to promote angiogenesis. This study aimed to investigate… 
2018
2018
MiR-142-3p Enhances Cell Viability and Inhibits Apoptosis by Targeting CDKN1B and TIMP3 Following Sciatic Nerve Injury
Background/Aims: MiRNAs are involved in phenotype modulation of neural cells after peripheral nerve injury. However, the roles of… 
2013
2013
Bovine lactoferricin induces TIMP-3 via the ERK1/2-Sp1 axis in human articular chondrocytes.
2011
2011
Molecular screening of the CYP4V2 gene in Bietti crystalline dystrophy that is associated with choroidal neovascularization
Purpose Bietti crystalline dystrophy (BCD) is an autosomal recessive disease characterized by intraretinal deposits of multiple… 
2010
2010
An Autocrine Linkage Between Matrix Metalloproteinase-14 and Tie-2 Via Ectodomain Shedding Modulates Angiopoietin-1–Dependent Function in Endothelial Cells
Objective—The angiopoietin (Ang)–Tie-2 system plays a critical role during fetal and adult angiogenesis. Herein, we explored the… 
2008
2008
Methylation of TIMP3 in esophageal squamous cell carcinoma.
AIM To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 (TIMP3) promoter and relate this… 
Highly Cited
2007
Highly Cited
2007
Expression profiles associated with aggressive behavior in Merkel cell carcinoma
Primary neuroendocrine carcinoma of the skin, or Merkel cell carcinoma, is the most aggressive cutaneous neoplasm. In spite of… 
2007
2007
Detection of gene expression in synovium of patients with osteoarthritis using a random sequencing method
Background The etiology of osteoarthritis (OA) is multifactorial and current research attributes it to a complex network of… 
Review
2001
Review
2001
Molecular genetics of macular degeneration
Macular degeneration is a leading cause of blindness that affects the aged population. The complexity of the molecular basis of… 
1996
1996
Cloning and expression of the cDNA encoding rat tissue inhibitor of metalloproteinase 3 (TIMP-3).
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