TIMP3 protein, human

Known as: tissue inhibitor of metalloproteinases-3, human, Mig-5 protein, human, Tissue Inhibitor of Metalloproteinases 3 
Metalloproteinase inhibitor 3 (221aa, ~24 kDa) is encoded by the human TIMP3 gene. This protein is involved in metalloproteinase inhibition.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Aberrantly expressed microRNAs (miRNAs) are involved in breast tumorigenesis. It is still unclear if and how miRNAs-221/222 are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
Malignant gliomas are the most common and the most lethal primary brain tumors in adults. Among malignant gliomas, 60%-80% show… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
OBJECTIVE Intervertebral disc degeneration is linked to loss of extracellular matrix (ECM), particularly the early loss of… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
UNLABELLED Cholangiocarcinomas (CCAs) are aggressive cancers, with high mortality and poor survival rates. Only radical surgery… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 2
Is this relevant?
2007
2007
ADAMTS-4 (aggrecanase-1) is a glutamyl endopeptidase capable of generating catabolic fragments of aggrecan analogous to those… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Drusen are extracellular deposits that accumulate below the retinal pigment epithelium on Bruch's membrane and are risk factors… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2000
2000
To preserve tissue integrity during the structural rearrangements that occur during central nervous system (CNS) development, an… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Tissue inhibitor of metalloproteinase-3 (TIMP-3) antagonizes matrix metalloproteinase activity and can suppress tumor growth… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
TNF-alpha converting enzyme (TACE; ADAM-17) is a membrane-bound disintegrin metalloproteinase that processes the membrane… (More)
Is this relevant?