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One-step Nucleic Acid Amplification for Intraoperative Detection of Lymph Node Metastasis in Breast Cancer Patients
TLDR
Clinical results indicate that the OSNA assay provides a useful intraoperative detection method of lymph node metastasis in breast cancer patients, and results similar to those of three-level histopathology.
Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma
TLDR
It is suggested that, of the four receptors, EGF-R and c-erbB-3 play important roles in the progression of HCC and were not recognized as independent prognostic factors by multivariate analysis.
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities
TLDR
The results indicate that AMAP1 is a component involved in invasive activities of different breast cancers, and provide new information regarding the possible therapeutic targets for prevention of breast cancer invasion and metastasis.
Molecular Detection of Lymph Node Metastases in Breast Cancer Patients: Results of a Multicenter Trial Using the One-Step Nucleic Acid Amplification Assay
TLDR
The OSNA assay can detect lymph node metastasis as accurately as can conventional pathology and thus can be an effective addition to or alternative for rapid intraoperative examination of SLNs.
Expression and prognostic roles of the G1‐S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence
TLDR
It is suggested that in HCC p27 is active against HCC progression in early phases and, possibly, hepatocarcinogenesis as a negative regulator and can be a novel prognostic marker for DFS.
Particle irradiation suppresses metastatic potential of cancer cells.
TLDR
It is suggested that particle irradiation suppresses metastatic potential even at lower doses, whereas photon irradiation promotes cell migration and invasive capabilities at lower dose level, and preclinical evidence that ion beam radiotherapy may be superior to conventional photon beam therapy in possible preventive effects on metastases of irradiated malignant tumor cells is provided.
Stromal Myofibroblasts Predict Disease Recurrence for Colorectal Cancer
TLDR
The results suggest that the abundance of myofibroblasts in cancer-associated stroma may be a useful indicator of disease recurrence after curative colorectal cancer surgery.
In situ tissue regeneration using a novel tissue-engineered, small-caliber vascular graft without cell seeding.
PACSIN3 Binds ADAM12/Meltrin α and Up-regulates Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor*
TLDR
The data indicate that PACSIN3 has a novel function as an up-regulator in the signaling of proHB-EGF shedding induced by TPA and angiotensin II.
The preventive effects of low-dose enteric-coated aspirin tablets on the development of colorectal tumours in Asian patients: a randomised trial
TLDR
Subgroup analysis revealed that subjects who were non-smokers, defined as those who had smoked in the past or who had never smoked, had a marked reduction in the number of recurrent tumours in the aspirin-treated group, consistent with those obtained from other randomised controlled trials in Western countries.
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