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Tissue Inhibitor of Metalloproteinase-2
Known as:
Tissue Inhibitor of Metalloproteinase 2
, Metalloproteinase-2 Tissue Inhibitor
, Tissue Inhibitor of Metalloproteinase-2 [Chemical/Ingredient]
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A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a…
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National Institutes of Health
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Related topics
Related topics
13 relations
Narrower (2)
111In-DTPA-N-TIMP-2
TIMP2 protein, human
In Blood
Process of secretion
TIMP2 gene
agonists
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Broader (2)
Matrix Metalloproteinase Inhibitors
Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Zahid Hussain
,
M. I. Khan
,
Muhammad Shahid
,
F. Almajhdi
Genetics and Molecular Research
2013
Corpus ID: 828499
DNA methylation is a fundamental epigenetic mechanism in regulating the expression of genes controlling crucial cell functions in…
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2007
2007
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
E. Vairaktaris
,
C. Yapijakis
,
+9 authors
E. Patsouris
Oncology Report
2007
Corpus ID: 15207877
The present study was performed in order to investigate the possible association of the -418 G/C polymorphism in the tissue…
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2005
2005
Protein profiles of bovine placenta derived from somatic cell nuclear transfer
Hong-Rye Kim
,
Jae Ku Kang
,
+5 authors
D. Jin
Proteomics
2005
Corpus ID: 20646295
Practical application of animal cloning by somatic cell nuclear transfer (SCNT) has been hampered by an extremely low success…
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2005
2005
Quantification of Tissue Inhibitor of Metalloproteinases 2 in Plasma from Healthy Donors and Cancer Patients
M. Larsen
,
Ross W. Stephens
,
+7 authors
Gunilla Høyer-Hansen
Scandinavian Journal of Immunology
2005
Corpus ID: 23359098
Tissue inhibitor of metalloproteinases (TIMP)‐2 is a highly conserved molecule, which binds both active and latent matrix…
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2004
2004
Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells.
Seong-Min Ahn
,
S. Jeong
,
Yeon-Soo Kim
,
Yeowon Sohn
,
A. Moon
Cancer Letters
2004
Corpus ID: 12096170
Highly Cited
2002
Highly Cited
2002
IL-4 Up-Regulates the Expression of Tissue Inhibitor of Metalloproteinase-2 in Dermal Fibroblasts Via the p38 Mitogen-Activated Protein Kinase-Dependent Pathway1
H. Ihn
,
K. Yamane
,
Y. Asano
,
M. Kubo
,
K. Tamaki
Journal of Immunology
2002
Corpus ID: 29236461
Tissue inhibitor of metalloproteinase-2 (TIMP-2) is a potent inhibitor of activated matrix metalloproteinases such as gelatinase…
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Highly Cited
2002
Highly Cited
2002
MT1‐MMP, but not secreted MMPs, influences the migration of human microvascular endothelial cells in 3‐dimensional collagen gels
T. Koike
,
R. Vernon
,
M. Hamner
,
E. Sadoun
,
M. Reed
Journal of Cellular Biochemistry
2002
Corpus ID: 37790350
Matrix metalloproteinases (MMPs) and their specific inhibitors the TIMPs play significant roles in angiogenesis. We investigated…
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Highly Cited
1999
Highly Cited
1999
The Specificity of TIMP-2 for Matrix Metalloproteinases Can Be Modified by Single Amino Acid Mutations*
Georgina S. Butler
,
M. Hutton
,
+4 authors
G. Murphy
Journal of Biological Chemistry
1999
Corpus ID: 2954712
Residues 1–127 of human TIMP-2 (N-TIMP-2), comprising three of the disulfide-bonded loops of the TIMP-2 molecule, is a discrete…
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1998
1998
The membrane-type-matrix metalloproteinase/matrix metalloproteinase-2/tissue inhibitor of metalloproteinase-2 system in periprosthetic connective-tissue remodeling in loose total-hip prostheses.
Michiaki Takagi
,
S. Santavirta
,
+4 authors
Konttinen Yt
Laboratory investigation; a journal of technical…
1998
Corpus ID: 22766570
The aim of the present study was to investigate the proteolytic potential and localization of matrix metalloproteinase (MMP)-2 in…
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Highly Cited
1993
Highly Cited
1993
Role and regulation of expression of 92‐kDa type‐IV collagenase (MMP‐9) in 2 invasive squamous‐cell‐carcinoma cell lines of the oral cavity
Jose C. Juarez
,
G. Clayman
,
+4 authors
D. Boyd
International Journal of Cancer
1993
Corpus ID: 12451698
The present study was undertaken to determine the role of the metalloproteinase MMP‐9 in the invasive phenotype of squamous‐cell…
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