Tissue Inhibitor of Metalloproteinase-2

Known as: Tissue Inhibitor of Metalloproteinase 2, Metalloproteinase-2 Tissue Inhibitor, Tissue Inhibitor of Metalloproteinase-2 [Chemical/Ingredient] 
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a… (More)
National Institutes of Health

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Topic mentions per year

1990-2018
05019902018

Papers overview

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2007
2007
Gene silencing via CpG island methylation in the promoter region is one of the mechanisms by which tumor suppressor genes are… (More)
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Highly Cited
2006
Highly Cited
2006
The tissue inhibitors of metalloproteinases (TIMPs) regulate matrix metalloproteinase activity required for cell migration… (More)
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2001
Highly Cited
2001
PURPOSE A disruption in the balance between the matrix metalloproteinases (MMPs) and their natural inhibitors, tissue inhibitors… (More)
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2000
Highly Cited
2000
Previous studies have shown that membrane type 1-matrix metalloproteinase (MT1-MMP) (MMP-14) initiates pro-MMP-2 activation in a… (More)
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1998
Highly Cited
1998
In interstitial lung diseases, deposition of extracellular matrix (ECM) in alveoli and degradation of ECM lead to pulmonary… (More)
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1998
Highly Cited
1998
BACKGROUND Matrix metalloproteinase-2 (MMP-2), which degrades the extracellular matrix or the basement membrane, has an essential… (More)
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1998
Highly Cited
1998
It has been proposed that tissue inhibitor of metalloproteinase-2 (TIMP-2), in stoichiometric concentrations, serves as an… (More)
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1997
Highly Cited
1997
The dissociation constants (Kd) of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 for the active and latent forms of… (More)
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1993
Highly Cited
1993
Tissue inhibitor of metalloproteinase-2 (TIMP-2), a protease inhibitor that binds to the latent and active forms of 72 kDa type… (More)
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1990
Highly Cited
1990
Human tissue inhibitor of metalloproteinase-2 (TIMP-2) was cloned and sequenced from an A2058 human melanoma cell cDNA library… (More)
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