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Ticrynafen

Known as: 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid, Tienilic acid, Acido tienilico 
A novel diuretic with uricosuric action. It has been proposed as an antihypertensive agent.
National Institutes of Health

Papers overview

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1989
1989
A stop-flow technique using pyrazinoic acid(PZO)-treated and -untreated rats was devised to evaluate drug effects on bi… 
1987
1987
5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (S-8666) was studied as a possible new uricosuric… 
1983
1983
A prospective evaluation was started in 1976 to study the influence of diuretics alone or combined with beta-blockers on serum… 
1980
1980
Effects of antihypertensive and uricosuric drugs were studied on the plasma and urinary levels of uric acid in oxonate-treated… 
1979
1979
Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the… 
1978
1978
A sensitive GLC assay for ticrynafen, a diuretic agent with uricosuric properties, and its two metabolites in urine, serum, and… 
1978
1978
Tienilic acid--2,3-dichloro-4-(2-thienyl-carbonyl)phenoxyacetic acid--is a new diuretic with uricosuric properties. Nineteen… 
1978
1978
Acute and chronic studies were performed on 6 bealthy human volunteers. Four subjects took a Single oral dose of tienilic acid 1…