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5-hydroxythienilic acid

Known as: 5-hydroxyticrynafen, 5-hydroxytienilic acid, Acetic acid, (2,3-dichloro-4-((5-hydroxy-2-thienyl)carbonyl)phenoxy)- 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Ticrynafen

Papers overview

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Highly Cited
1994
Highly Cited
1994
Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid.
Oxidation of tienilic acid (TA) by microsomes of yeast expressing two closely related human liver cytochrome P-450s (P450), P450… 
Highly Cited
1990
Highly Cited
1990
Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
1990
1990
Hydroxylation of the thiophene ring by hepatic monooxygenases. Evidence for 5-hydroxylation of 2-aroylthiophenes as a general metabolic pathway using a simple UV-visible assay.
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