Uricosuric Agents

Known as: Agents, Uricosuric, Hyperuricaemia Agents, Uricosuric Agent 
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
051019492017

Papers overview

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Highly Cited
2006
Highly Cited
2006
The worldwide epidemic of metabolic syndrome correlates with an elevation in serum uric acid as well as a marked increase in… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Allopurinol has been shown to improve endothelial function in chronic heart failure. This study aimed to establish its… (More)
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2005
2005
Benzbromarone has been reported to increase the renal clearance of oxypurinol, an active metabolite of allopurinol. We examined… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk… (More)
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Highly Cited
2001
Highly Cited
2001
An elevation in circulating serum uric acid is strongly associated with the development of hypertension and renal disease, but… (More)
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1999
1999
OBJECTIVE To clarify the mechanism(s) for the interaction between warfarin and benzbromarone, a uricosuric agent, and to predict… (More)
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1997
1997
Inhibition of [14C]-urate uptake by uricosuric and antiuricosuric agents was investigated in human brush-border membrane vesicles… (More)
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1980
1980
To differentiate between extrarenal and renal causes of hyperuricaemia and gout, clearances of urate and creatinine were… (More)
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1973
1973
The acute effects of intravenous (i.v.) probenecid and chlorothiazide on renal urate handling were investigated in paired studies… (More)
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1957
1957
Experience gained during the past 7 years with the prolonged administration of probenecid (Pascale, Dubin, and Hoffman, 1952… (More)
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