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Benzbromarone

Known as: Benzbromaron, Benzbromarone [Chemical/Ingredient], Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)- 
Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (10)

1'-hydroxybenzbromarone1'-oxobenzbromarone6-hydroxybenzbromaroneAcifugan
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Uricosuric Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Effects of new‐generation inhibitors of the calcium‐activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract
High‐throughput screening of compound libraries using genetically encoded fluorescent biosensors has identified several second… 
Review
2011
Review
2011
Management of asymptomatic hyperuricaemia in patients with chronic kidney disease by Japanese nephrologists: A questionnaire survey
Aim:  Hyperuricaemia is associated with chronic kidney disease (CKD) progression and cardiovascular events (CVE). In a US study… 
2010
2010
The synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP…
2008
2008
Modulation of sinusoidal and canalicular elimination of bilirubin‐glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes
Aim:  Drug‐induced hyperbilirubinemia has been shown to often be derived from modulation of the expression and activity of… 
2007
2007
Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.
2005
2005
CYP2C9 Genotype-Dependent Effects on in Vitro Drug-Drug Interactions: Switching of Benzbromarone Effect from Inhibition to Activation in the CYP2C9.3 Variant
The CYP2C9.3 variant exhibits marked decreases in substrate turnover compared with the wild-type enzyme, but little is known… 
1994
1994
Comparison of derivatization procedures for the determination of diuretics in urine by gas chromatography-mass spectrometry.
1990
1990
Toxicological studies on a benzofuran derivative. III. Comparison of peroxisome proliferation in rat and human hepatocytes in primary culture.
1976
1976
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
  • Yu Tf
  • 1976
  • Corpus ID: 77592341
Abstract Benzbromarone, a potent uricosuric agent, is a benzofuran derivative with a bromine on the 3rd and 5th positions of the… 
1972
1972
Metabolism of benzbromarone in man
SummaryBenzbromarone, uniformly labelled with tritium by the Wilzbach procedure, was administered orally to 10 patients. No… 
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