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Apazone

Known as: 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, Apazone [Chemical/Ingredient] 
An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (4)

6-hydroxyazapropazoneProlixanRheumoxTolyprin

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalUricosuric Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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1987
1987
Comparative trial of azapropazone and indomethacin plus allopurinol in acute gout and hyperuricaemia.
This study compared the effects of azapropazone and indomethacin plus allopurinol in the management of acute gout and… 
1983
1983
Preliminary studies with azapropazone in gout and hyperuricaemia.
Eight patients with acute gouty arthritis were treated with high dose oral azapropazone 600 mg qds in an open study in order to… 
1981
1981
Plasma protein binding of azapropazone in patients with kidney and liver disease.
1 The free fraction of azapropazone in the plasma of 37 healthy volunteers ranged from 0.0027 to 0.0070 (0.0044 +/- 0.0009, mean… 
1981
1981
Anticonvulsant intoxication precipitated by azapropazone
A patient is reported who developed a hitherto unrecognized drug interaction between azapropazone and anticonvulsants which led… 
1981
1981
Clinical therapeutic trial of aspirin and azapropazone in rheumatoid arthritis when prescribed singly and in combination.
A double-blind, crossover trial was carried out to assess the clinical efficacy of 3.6 g aspirin, 1200 mg azapropazone and the… 
1976
1976
Long-term use of azapropazone in rheumatoid conditions.
In an open assessment of azapropazone, 51 patients with rheumatoid disorders, mainly rheumatoid arthritis, were treated… 
1976
1976
Clinical assessment of azapropazone in rheumatoid arthritis.
Azapropazone was investigated in a 2-week double-blind clinical out-patient trial against placebo in 23 patients with definite… 
1976
1976
A comparative study of azapropazone and indomethacin in the treatment of rheumatoid arthritis.
A double-blind crossover trial in 50 patients with rheumatoid arthritis was carried out to compare the clinical effectiveness of… 
1976
1976
A comparative study of azapropazone and ibuprofen in the treatment of osteoarthrosis of the knee
SummaryA double-blind crossover study in 41 patients with knee joint osteoarthrosis was carried out to compare the efficacy of… 
1974
1974
Preliminary clinical evaluation of azapropazone in rheumatoid arthritis.
SummaryAzapropazone, a new non-steroidal anti-inflammatory drug, was investigated in a single-blind, crossover clinical out…